A Review of Magnetic Resonance Spectroscopy Studies in Marijuana using Adolescents and Adults

DSpace/Manakin Repository

A Review of Magnetic Resonance Spectroscopy Studies in Marijuana using Adolescents and Adults

Citable link to this page

 

 
Title: A Review of Magnetic Resonance Spectroscopy Studies in Marijuana using Adolescents and Adults
Author: Sneider, Jennifer T; Mashhoon, Yasmin; Silveri, Marisa M

Note: Order does not necessarily reflect citation order of authors.

Citation: Sneider, Jennifer T, Yasmin Mashhoon, and Marisa M Silveri. 2013. “A Review of Magnetic Resonance Spectroscopy Studies in Marijuana using Adolescents and Adults.” Journal of addiction research & therapy Suppl 4 (1): 010. doi:10.4172/2155-6105.S4-010. http://dx.doi.org/10.4172/2155-6105.S4-010.
Full Text & Related Files:
Abstract: Marijuana (MJ) remains the most widely used illicit drug of abuse, and accordingly, is associated with adverse effects on mental and physical health, and neurocognitive decline. Studies investigating the neurobiology of underlying MJ effects have demonstrated structural and functional alterations in brain areas that contain moderate to high concentrations of cannabinoid (CB1) receptors and that are implicated in MJ-related cognitive decrements. Proton magnetic resonance spectroscopy (1H MRS), a non-invasive imaging technique used to assess neurochemistry, has been widely applied to probe a variety of substance-abusing populations. To date, however, there is a relative paucity of MRS published studies characterizing changes in neurometabolite concentrations in MJ users. Thus, the current review provides a summary of data from the eight existing MRS studies of MJ use in adolescents and adults, as well as interpretations and implications of study findings. Future MRS studies that address additional factors such as sex differences, onset and duration of use, abstinence and age, are warranted, and would lead to a more thorough characterization of potential neurochemical correlates of chronic MJ use, which would fill critical gaps in the existing literature.
Published Version: doi:10.4172/2155-6105.S4-010
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936252/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11879895
Downloads of this work:

Show full Dublin Core record

This item appears in the following Collection(s)

 
 

Search DASH


Advanced Search
 
 

Submitters