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dc.contributor.authorQi, Haoen_US
dc.contributor.authorGhodousi, Majiden_US
dc.contributor.authorDu, Yananen_US
dc.contributor.authorGrun, Caseyen_US
dc.contributor.authorBae, Hojaeen_US
dc.contributor.authorYin, Pengen_US
dc.contributor.authorKhademhosseini, Alien_US
dc.date.accessioned2014-04-11T14:12:12Z
dc.date.issued2013en_US
dc.identifier.citationQi, Hao, Majid Ghodousi, Yanan Du, Casey Grun, Hojae Bae, Peng Yin, and Ali Khademhosseini. 2013. “DNA directed self-assembly of shape-controlled hydrogels.” Nature communications 4 (1): 2275. doi:10.1038/ncomms3275. http://dx.doi.org/10.1038/ncomms3275.en
dc.identifier.issn2041-1723en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:12064445
dc.description.abstractUsing DNA as programmable, sequence specific ‘glues’, shape-controlled hydrogel units are self-assembled into prescribed structures. Here we report that aggregates are produced using hydrogel cubes with edge length ranging from 30 micrometers to 1 millimeter, demonstrating assembly across scales. In a simple one-pot agitation reaction, 25 dimers are constructed in parallel from 50 distinct hydrogel cube species, demonstrating highly multiplexed assembly. Using hydrogel cuboids displaying face-specific DNA glues, diverse structures are achieved in aqueous and in interfacial agitation systems. These include dimers, extended chains, and open network structures in an aqueous system; and dimers, chains of fixed length, T-junctions, and square shapes in the interfacial system, demonstrating the versatility of the assembly system.en
dc.language.isoen_USen
dc.relation.isversionofdoi:10.1038/ncomms3275en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768014/pdf/en
dash.licenseLAAen_US
dc.titleDNA directed self-assembly of shape-controlled hydrogelsen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalNature communicationsen
dash.depositing.authorYin, Pengen_US
dc.date.available2014-04-11T14:12:12Z
dc.identifier.doi10.1038/ncomms3275*
dash.contributor.affiliatedKhademhosseini, Ali
dash.contributor.affiliatedYin, Peng


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