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dc.contributor.authorCraig, Alister G.
dc.contributor.authorGrau, Georges E.
dc.contributor.authorJanse, Chris
dc.contributor.authorKazura, James W.
dc.contributor.authorMilner, Danny Arnold
dc.contributor.authorBarnwell, John W.
dc.contributor.authorTurner, Gareth
dc.contributor.authorLanghorne, Jean
dc.date.accessioned2014-04-28T18:45:50Z
dc.date.issued2012
dc.identifier.citationCraig, Alister G., Georges E. Grau, Chris Janse, James W. Kazura, Danny Arnold Milner, John W. Barnwell, Gareth Turner, and Jean Langhorne. 2012. “The Role of Animal Models for Research on Severe Malaria.” PLoS Pathogens 8(2) (February 2): e1002401. doi:10.1371/journal.ppat.1002401. http://dx.doi.org/10.1371/journal.ppat.1002401.en_US
dc.identifier.issn1553-7366en_US
dc.identifier.issn1553-7374en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:12117600
dc.description.abstractIn light of the recent controversies over the role of animal models for research into the development of new treatments for severe malaria, particularly cerebral disease, a group of scientists came together to discuss the relative merits of a range of animal models and their overlap with the complex clinical syndromes of human disease. While it was not possible to fully resolve differences over the utility of the Plasmodium berghei ANKA model of experimental cerebral malaria, the meeting did bring the two research communities closer together to identify further work to provide information needed to validate the model and revitalise the development of other animal models displaying features of human pathology. The driving force behind this was the desire to ensure better translation of experimental findings into effective treatments for severe malaria.en_US
dc.language.isoen_USen_US
dc.publisherPublic Library of Scienceen_US
dc.relation.isversionofdoi:10.1371/journal.ppat.1002401en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pubmed/22319438en_US
dash.licenseLAA
dc.subjectanemiaen_US
dc.subjectanimal modelsen_US
dc.subjectcerebral malariaen_US
dc.subjectmalariaen_US
dc.subjectmalarial parasitesen_US
dc.subjectparasitic diseasesen_US
dc.subjectplasmodiumen_US
dc.subjectrodentsen_US
dc.titleThe Role of Animal Models for Research on Severe Malariaen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalPLoS Pathogensen_US
dash.depositing.authorMilner, Danny Arnold
dc.date.available2014-04-28T18:45:50Z
dc.identifier.doi10.1371/journal.ppat.1002401*
dash.contributor.affiliatedMilner, Danny


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