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dc.contributor.authorMack, Hildegard I. D.en_US
dc.contributor.authorMunger, Karlen_US
dc.date.accessioned2014-05-06T16:17:52Z
dc.date.issued2012en_US
dc.identifier.citationMack, Hildegard I. D., and Karl Munger. 2012. “Modulation of Autophagy-Like Processes by Tumor Viruses.” Cells 1 (3): 204-247. doi:10.3390/cells1030204. http://dx.doi.org/10.3390/cells1030204.en
dc.identifier.issn2073-4409en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:12152942
dc.description.abstractAutophagy is an intracellular degradation pathway for long-lived proteins and organelles. This process is activated above basal levels upon cell intrinsic or environmental stress and dysregulation of autophagy has been linked to various human diseases, including those caused by viral infection. Many viruses have evolved strategies to directly interfere with autophagy, presumably to facilitate their replication or to escape immune detection. However, in some cases, modulation of autophagy appears to be a consequence of the virus disturbing the cell’s metabolic signaling networks. Here, we summarize recent advances in research at the interface of autophagy and viral infection, paying special attention to strategies that human tumor viruses have evolved.en
dc.language.isoen_USen
dc.publisherMDPIen
dc.relation.isversionofdoi:10.3390/cells1030204en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901111/pdf/en
dash.licenseLAAen_US
dc.subjectautophagyen
dc.subjectcanceren
dc.subjectEpstein–Barr virusen
dc.subjecthepatitis B virusen
dc.subjecthepatitis C virusen
dc.subjecthuman papillomavirusen
dc.subjecthuman T-lymphotropic virus 1en
dc.subjectKaposi’s sarcoma-associated herpesvirusen
dc.subjectMerkel cell polyomavirusen
dc.titleModulation of Autophagy-Like Processes by Tumor Virusesen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalCellsen
dash.depositing.authorMunger, Karlen_US
dc.date.available2014-05-06T16:17:52Z
dc.identifier.doi10.3390/cells1030204*
dash.contributor.affiliatedMunger, Karl


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