New insights into BRCA1 function and its role in cancer development

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New insights into BRCA1 function and its role in cancer development

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Title: New insights into BRCA1 function and its role in cancer development
Author: Hill, Sarah James
Citation: Hill, Sarah James. 2014. New insights into BRCA1 function and its role in cancer development. Doctoral dissertation, Harvard University.
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Abstract: BRCA1 is a breast and ovarian tumor suppressor. The role of BRCA1 in the repair of double strand DNA breaks by homologous recombination [HR] is its best understood function and the function most often implicated in BRCA1 breast cancer suppression. However, BRCA1 has less well defined roles in multiple other molecular processes.
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:12274574
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