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dc.contributor.authorSriram, Sudhiren_US
dc.contributor.authorCondie, Joyen_US
dc.contributor.authorSchreiber, Michael D.en_US
dc.contributor.authorBatton, Daniel G.en_US
dc.contributor.authorShah, Bhaveshen_US
dc.contributor.authorBose, Carlen_US
dc.contributor.authorLaughon, Matthewen_US
dc.contributor.authorVan Marter, Linda J.en_US
dc.contributor.authorAllred, Elizabeth N.en_US
dc.contributor.authorLeviton, Alanen_US
dc.date.accessioned2014-07-07T17:01:47Z
dc.date.issued2014en_US
dc.identifier.citationSriram, Sudhir, Joy Condie, Michael D. Schreiber, Daniel G. Batton, Bhavesh Shah, Carl Bose, Matthew Laughon, Linda J. Van Marter, Elizabeth N. Allred, and Alan Leviton. 2014. “Early Blood Gas Predictors of Bronchopulmonary Dysplasia in Extremely Low Gestational Age Newborns.” International Journal of Pediatrics 2014 (1): 210218. doi:10.1155/2014/210218. http://dx.doi.org/10.1155/2014/210218.en
dc.identifier.issn1687-9740en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:12406555
dc.description.abstractAim. To determine among infants born before the 28th week of gestation to what extent blood gas abnormalities during the first three postnatal days provide information about the risk of bronchopulmonary dysplasia (BPD). Methods:. We studied the association of extreme quartiles of blood gas measurements (hypoxemia, hyperoxemia, hypocapnea, and hypercapnea) in the first three postnatal days, with bronchopulmonary dysplasia, among 906 newborns, using multivariable models adjusting for potential confounders. We approximated NIH criteria by classifying severity of BPD on the basis of the receipt of any O2 on postnatal day 28 and at 36 weeks PMA and assisted ventilation. Results:. In models that did not adjust for ventilation, hypoxemia was associated with increased risk of severe BPD and very severe BPD, while infants who had hypercapnea were at increased risk of very severe BPD only. In contrast, infants who had hypocapnea were at reduced risk of severe BPD. Including ventilation for 14 or more days eliminated the associations with hypoxemia and with hypercapnea and made the decreased risk of very severe BPD statistically significant. Conclusions:. Among ELGANs, recurrent/persistent blood gas abnormalities in the first three postnatal days convey information about the risk of severe and very severe BPD.en
dc.language.isoen_USen
dc.publisherHindawi Publishing Corporationen
dc.relation.isversionofdoi:10.1155/2014/210218en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052060/pdf/en
dash.licenseLAAen_US
dc.titleEarly Blood Gas Predictors of Bronchopulmonary Dysplasia in Extremely Low Gestational Age Newbornsen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalInternational Journal of Pediatricsen
dash.depositing.authorVan Marter, Linda J.en_US
dc.date.available2014-07-07T17:01:47Z
dc.identifier.doi10.1155/2014/210218*
dash.contributor.affiliatedVan Marter, Linda
dash.contributor.affiliatedAllred, Elizabeth
dash.contributor.affiliatedLeviton, Alan


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