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dc.contributor.authorSchwarzkopf, Ranen_US
dc.contributor.authorMikhael, Bassemen_US
dc.contributor.authorWright, Elizabethen_US
dc.contributor.authorEstok, Daniel Men_US
dc.contributor.authorKatz, Jeffrey Nen_US
dc.date.accessioned2014-07-07T17:01:58Z
dc.date.issued2014en_US
dc.identifier.citationSchwarzkopf, Ran, Bassem Mikhael, Elizabeth Wright, Daniel M Estok, and Jeffrey N Katz. 2014. “Treatment Failure Among Infected Periprosthetic Total Hip Arthroplasty Patients.” The Open Orthopaedics Journal 8 (1): 118-124. doi:10.2174/1874325020140515002. http://dx.doi.org/10.2174/1874325020140515002.en
dc.identifier.issn1874-3250en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:12406577
dc.description.abstractTwo-stage revision has been shown to be the most successful treatment in eradicating deep infection following total hiparthroplasty. We identified 62 patients treated by a two-stage revision. We defined “successful revision” as negative intraoperative cultures and no further infection-related procedure. We defined “eradication of infection” on the basis of negative cultures and clinical diagnosis at least one year after 2nd stage procedure. After a mean follow up of 2.7 years, eradication of the infection was documented in 91.1%, and a successful two-stage revision in 85.7% of patients. We observed no association between higher pre-reimplantation levels of ESR and C-reactive protein and lower likelihood of successful two-stage revision. We found an association between a history of another previous infected prosthetic joint and a failed 2nd stage procedure. Failure to achieve eradication of infection and successful two-stage revision occurs infrequently. Patients with prior history of a previous prosthetic joint infection are at higher risk of failure.en
dc.language.isoen_USen
dc.publisherBentham Openen
dc.relation.isversionofdoi:10.2174/1874325020140515002en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066371/pdf/en
dash.licenseLAAen_US
dc.subjectHip arthroplastyen
dc.subjectmodular antibiotic cement spaceren
dc.subjectperiprosthetic infectionen
dc.subjecttwo-stage revision surgery.en
dc.titleTreatment Failure Among Infected Periprosthetic Total Hip Arthroplasty Patientsen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalThe Open Orthopaedics Journalen
dash.depositing.authorMikhael, Bassemen_US
dc.date.available2014-07-07T17:01:58Z
dc.identifier.doi10.2174/1874325020140515002*
dash.contributor.affiliatedEstok, Daniel
dash.contributor.affiliatedMikhael, Bassem
dash.contributor.affiliatedWright, Elizabeth
dash.contributor.affiliatedKatz, Jeffrey


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