dc.contributor.author | Schwarzkopf, Ran | en_US |
dc.contributor.author | Mikhael, Bassem | en_US |
dc.contributor.author | Wright, Elizabeth | en_US |
dc.contributor.author | Estok, Daniel M | en_US |
dc.contributor.author | Katz, Jeffrey N | en_US |
dc.date.accessioned | 2014-07-07T17:01:58Z | |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | Schwarzkopf, Ran, Bassem Mikhael, Elizabeth Wright, Daniel M Estok, and Jeffrey N Katz. 2014. “Treatment Failure Among Infected Periprosthetic Total Hip Arthroplasty Patients.” The Open Orthopaedics Journal 8 (1): 118-124. doi:10.2174/1874325020140515002. http://dx.doi.org/10.2174/1874325020140515002. | en |
dc.identifier.issn | 1874-3250 | en |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:12406577 | |
dc.description.abstract | Two-stage revision has been shown to be the most successful treatment in eradicating deep infection following total hiparthroplasty. We identified 62 patients treated by a two-stage revision. We defined “successful revision” as negative intraoperative cultures and no further infection-related procedure. We defined “eradication of infection” on the basis of negative cultures and clinical diagnosis at least one year after 2nd stage procedure. After a mean follow up of 2.7 years, eradication of the infection was documented in 91.1%, and a successful two-stage revision in 85.7% of patients. We observed no association between higher pre-reimplantation levels of ESR and C-reactive protein and lower likelihood of successful two-stage revision. We found an association between a history of another previous infected prosthetic joint and a failed 2nd stage procedure. Failure to achieve eradication of infection and successful two-stage revision occurs infrequently. Patients with prior history of a previous prosthetic joint infection are at higher risk of failure. | en |
dc.language.iso | en_US | en |
dc.publisher | Bentham Open | en |
dc.relation.isversionof | doi:10.2174/1874325020140515002 | en |
dc.relation.hasversion | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066371/pdf/ | en |
dash.license | LAA | en_US |
dc.subject | Hip arthroplasty | en |
dc.subject | modular antibiotic cement spacer | en |
dc.subject | periprosthetic infection | en |
dc.subject | two-stage revision surgery. | en |
dc.title | Treatment Failure Among Infected Periprosthetic Total Hip Arthroplasty Patients | en |
dc.type | Journal Article | en_US |
dc.description.version | Version of Record | en |
dc.relation.journal | The Open Orthopaedics Journal | en |
dash.depositing.author | Mikhael, Bassem | en_US |
dc.date.available | 2014-07-07T17:01:58Z | |
dc.identifier.doi | 10.2174/1874325020140515002 | * |
dash.contributor.affiliated | Estok, Daniel | |
dash.contributor.affiliated | Mikhael, Bassem | |
dash.contributor.affiliated | Wright, Elizabeth | |
dash.contributor.affiliated | Katz, Jeffrey | |