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dc.contributor.authorBergan, Joseph Fen_US
dc.contributor.authorBen-Shaul, Yoramen_US
dc.contributor.authorDulac, Catherineen_US
dc.date.accessioned2014-07-07T17:02:49Z
dc.date.issued2014en_US
dc.identifier.citationBergan, Joseph F, Yoram Ben-Shaul, and Catherine Dulac. 2014. “Sex-specific processing of social cues in the medial amygdala.” eLife 3 (1): e02743. doi:10.7554/eLife.02743. http://dx.doi.org/10.7554/eLife.02743.en
dc.identifier.issn2050-084Xen
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:12406644
dc.description.abstractAnimal–animal recognition within, and across species, is essential for predator avoidance and social interactions. Despite its essential role in orchestrating responses to animal cues, basic principles of information processing by the vomeronasal system are still unknown. The medial amygdala (MeA) occupies a central position in the vomeronasal pathway, upstream of hypothalamic centers dedicated to defensive and social responses. We have characterized sensory responses in the mouse MeA and uncovered emergent properties that shed new light onto the transformation of vomeronasal information into sex- and species-specific responses. In particular, we show that the MeA displays a degree of stimulus selectivity and a striking sexually dimorphic sensory representation that are not observed in the upstream relay of the accessory olfactory bulb (AOB). Furthermore, our results demonstrate that the development of sexually dimorphic circuits in the MeA requires steroid signaling near the time of puberty to organize the functional representation of sensory stimuli. DOI: http://dx.doi.org/10.7554/eLife.02743.001en
dc.language.isoen_USen
dc.publishereLife Sciences Publications, Ltden
dc.relation.isversionofdoi:10.7554/eLife.02743en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038839/pdf/en
dash.licenseLAAen_US
dc.subjectmedial amygdalaen
dc.subjectsensory representationen
dc.subjectsexual dimorphismen
dc.subjectvomeronasal systemen
dc.subjectpheromonesen
dc.subjectbehavioren
dc.subjectmouseen
dc.titleSex-specific processing of social cues in the medial amygdalaen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journaleLifeen
dash.depositing.authorBergan, Joseph Fen_US
dc.date.available2014-07-07T17:02:49Z
dc.identifier.doi10.7554/eLife.02743*
dash.contributor.affiliatedBergan, Joseph F
dash.contributor.affiliatedDulac, Catherine


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