Epigenetic modifications: basic mechanisms and role in cardiovascular disease (2013 Grover Conference series)

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Epigenetic modifications: basic mechanisms and role in cardiovascular disease (2013 Grover Conference series)

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Title: Epigenetic modifications: basic mechanisms and role in cardiovascular disease (2013 Grover Conference series)
Author: Loscalzo, Joseph; Handy, Diane E.

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Citation: Loscalzo, Joseph, and Diane E. Handy. 2014. “Epigenetic modifications: basic mechanisms and role in cardiovascular disease (2013 Grover Conference series).” Pulmonary Circulation 4 (2): 169-174. doi:10.1086/675979. http://dx.doi.org/10.1086/675979.
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Abstract: Abstract Epigenetics refers to heritable traits that are not a consequence of DNA sequence. Three classes of epigenetic regulation exist: DNA methylation, histone modification, and noncoding RNA action. In the cardiovascular system, epigenetic regulation affects development, differentiation, and disease propensity or expression. Defining the determinants of epigenetic regulation offers opportunities for novel strategies for disease prevention and treatment.
Published Version: doi:10.1086/675979
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070783/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:12717375
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