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dc.contributor.authorKim, Hye Wonen_US
dc.contributor.authorKim, Yang-Hyunen_US
dc.contributor.authorHan, Kyungdoen_US
dc.contributor.authorNam, Ga Eunen_US
dc.contributor.authorKim, Gwang Seonen_US
dc.contributor.authorHan, Byoung-Ducken_US
dc.contributor.authorLee, Annaen_US
dc.contributor.authorAhn, Ji Yongen_US
dc.contributor.authorKo, Byung Joonen_US
dc.date.accessioned2014-08-13T13:59:30Z
dc.date.issued2014en_US
dc.identifier.citationKim, Hye Won, Yang-Hyun Kim, Kyungdo Han, Ga Eun Nam, Gwang Seon Kim, Byoung-Duck Han, Anna Lee, Ji Yong Ahn, and Byung Joon Ko. 2014. “Atrophic Gastritis: A Related Factor for Osteoporosis in Elderly Women.” PLoS ONE 9 (7): e101852. doi:10.1371/journal.pone.0101852. http://dx.doi.org/10.1371/journal.pone.0101852.en
dc.identifier.issn1932-6203en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:12717489
dc.description.abstractPurpose Osteoporosis poses a great threat to the aging society. Hypochlorhydric or achlorhydric conditions are risk factors for osteoporosis. Atrophic gastritis also decreases gastric acid production; however, the role of atrophic gastritis as a related factor for osteoporosis is unclear. We investigated the relationship between atrophic gastritis and osteoporosis in postmenopausal women over 60 years of age. Subjects and Methods A total of 401 postmenopausal women were included in this cross-sectional study, which was conducted during their medical check-ups. Bone mineral densitometry was measured using a dual energy X-ray absorptiometry. Atrophic gastritis was defined endoscopically if gastric mucosa in the antrum and the body were found to be atrophied and thinned and submucosal vessels could be well visualized. Results: The proportion of people with atrophic gastritis was higher in the osteoporotic group than in the group without osteoporosis. A linear relationship was observed in the proportion of atrophic gastritis according to the categories of normal, osteopenia, and osteoporosis at the lumbar spine (p for trend = 0.039) and femur (p for trend = 0.001). A multiple logistic regression analysis revealed that the presence of atrophic gastritis was associated with an increased odds of osteoporosis after adjusting for age, body mass index, triglyceride, high-density lipoprotein cholesterol, alcohol consumption, and smoking status (odds ratio 1.89, 95% confidence interval 1.15–3.11). Conclusions: Atrophic gastritis is associated with an increased likelihood of osteoporosis in Korean elderly women.en
dc.language.isoen_USen
dc.publisherPublic Library of Scienceen
dc.relation.isversionofdoi:10.1371/journal.pone.0101852en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087012/pdf/en
dash.licenseLAAen_US
dc.subjectMedicine and Health Sciencesen
dc.subjectAnatomyen
dc.subjectBoneen
dc.subjectBone Densityen
dc.subjectGastroenterology and Hepatologyen
dc.subjectGastritisen
dc.subjectWomen's Healthen
dc.subjectOsteopenia and Osteoporosisen
dc.subjectSocial Sciencesen
dc.subjectSociologyen
dc.subjectSocial Stratificationen
dc.subjectSocially Disadvantaged Peopleen
dc.titleAtrophic Gastritis: A Related Factor for Osteoporosis in Elderly Womenen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalPLoS ONEen
dc.date.available2014-08-13T13:59:30Z
dc.identifier.doi10.1371/journal.pone.0101852*
dash.authorsorderedfalse


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