Androgen receptor functions in prostate cancer development and progression

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Androgen receptor functions in prostate cancer development and progression

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Title: Androgen receptor functions in prostate cancer development and progression
Author: Balk, Steven P
Citation: Balk, Steven P. 2014. “Androgen receptor functions in prostate cancer development and progression.” Asian Journal of Andrology 16 (4): 561-564. doi:10.4103/1008-682X.126396. http://dx.doi.org/10.4103/1008-682X.126396.
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Abstract: The androgen receptor (AR) is critical for the normal development of prostate and for its differentiated functions. The consistent expression of AR in prostate cancer (PCa), and its continued activity in PCa that relapse after androgen deprivation therapy (castration-resistant prostate cancer (CRPC)), indicate that at least a subset of these genes are also critical for PCa development and progression. This review addressed AR regulated genes that may be critical for PCa, and how AR may acquire new functions during PCa development and progression.
Published Version: doi:10.4103/1008-682X.126396
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104081/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:12717543
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