Discovering cancer immunotherapy targets in vivo

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Discovering cancer immunotherapy targets in vivo

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Title: Discovering cancer immunotherapy targets in vivo
Author: Zhou, Penghui; Wucherpfennig, Kai W

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Citation: Zhou, Penghui, and Kai W Wucherpfennig. 2014. “Discovering cancer immunotherapy targets in vivo.” Oncoimmunology 3 (1): e28500. doi:10.4161/onci.28500. http://dx.doi.org/10.4161/onci.28500.
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Abstract: A key challenge facing the cancer immunology field is the discovery of the most suitable targets for therapeutic intervention. We recently reported a novel RNA-interference (RNAi)-based approach for systematic discovery of such targets in the tumor microenvironment in vivo utilizing pooled shRNA libraries as a screening tool. Here, we discuss applying this unbiased method to develop innovative cancer therapeutics.
Published Version: doi:10.4161/onci.28500
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063151/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:12717575
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