Controlling Airborne Cues to Study Small Animal Navigation

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Controlling Airborne Cues to Study Small Animal Navigation

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Title: Controlling Airborne Cues to Study Small Animal Navigation
Author: Gershow, Marc; Berck, Matthew E; Mathew, Dennis; Luo, Linjiao; Kane, Elizabeth Anne; Carlson, John R; Samuel, Aravinthan DT

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Citation: Gershow, Marc, Matthew Berck, Dennis Mathew, Linjiao Luo, Elizabeth A. Kane, John R. Carlson, and Aravinthan D. T. Samuel. 2012. Controlling Airborne Cues to Study Small Animal Navigation. Nature Methods 9, no. 3: 290–296.
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Abstract: Small animals such as nematodes and insects analyze airborne chemical cues to infer the direction of favorable and noxious locations. In these animals, the study of navigational behavior evoked by airborne cues has been limited by the difficulty of precisely controlling stimuli. We present a system that can be used to deliver gaseous stimuli in defined spatial and temporal patterns to freely moving small animals. We used this apparatus, in combination with machine-vision algorithms, to assess and quantify navigational decision making of Drosophila melanogaster larvae in response to ethyl acetate (a volatile attractant) and carbon dioxide (a gaseous repellant).
Published Version: doi:10.1038/nmeth.1853
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513333/
http://scholar.harvard.edu/files/aravisamuel/files/nature_methods_2012_gershow.pdf
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:12872179
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