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dc.contributor.authorCornelis, Marilyn C.en_US
dc.contributor.authorChiuve, Stephanie E.en_US
dc.contributor.authorGlymour, M. Mariaen_US
dc.contributor.authorChang, Shun-Chiaoen_US
dc.contributor.authorTchetgen Tchetgen, Eric J.en_US
dc.contributor.authorLiang, Limingen_US
dc.contributor.authorKoenen, Karestan C.en_US
dc.contributor.authorRimm, Eric B.en_US
dc.contributor.authorKawachi, Ichiroen_US
dc.contributor.authorKubzansky, Laura D.en_US
dc.date.accessioned2014-10-01T14:27:53Z
dc.date.issued2014en_US
dc.identifier.citationCornelis, Marilyn C., Stephanie E. Chiuve, M. Maria Glymour, Shun-Chiao Chang, Eric J. Tchetgen Tchetgen, Liming Liang, Karestan C. Koenen, Eric B. Rimm, Ichiro Kawachi, and Laura D. Kubzansky. 2014. “Bachelors, Divorcees, and Widowers: Does Marriage Protect Men from Type 2 Diabetes?” PLoS ONE 9 (9): e106720. doi:10.1371/journal.pone.0106720. http://dx.doi.org/10.1371/journal.pone.0106720.en
dc.identifier.issn1932-6203en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:12987251
dc.description.abstractWhile research has suggested that being married may confer a health advantage, few studies to date have investigated the role of marital status in the development of type 2 diabetes. We examined whether men who are not married have increased risk of incident type 2 diabetes in the Health Professionals Follow-up Study. Men (n = 41,378) who were free of T2D in 1986, were followed for ≤22 years with biennial reports of T2D, marital status and covariates. Cox proportional hazard models were used to compare risk of incident T2D by marital status (married vs unmarried and married vs never married, divorced/separated, or widowed). There were 2,952 cases of incident T2D. Compared to married men, unmarried men had a 16% higher risk of developing T2D (95%CI:1.04,1.30), adjusting for age, family history of diabetes, ethnicity, lifestyle and body mass index (BMI). Relative risks (RR) for developing T2D differed for divorced/separated (1.09 [95%CI: 0.94,1.27]), widowed (1.29 [95%CI:1.06,1.57]), and never married (1.17 [95%CI:0.91,1.52]) after adjusting for age, family history of diabetes and ethnicity. Adjusting for lifestyle and BMI, the RR for T2D associated with widowhood was no longer significant (RR:1.16 [95%CI:0.95,1.41]). When allowing for a 2-year lag period between marital status and disease, RRs of T2D for widowers were augmented and borderline significant (RR:1.24 [95%CI:1.00,1.54]) after full adjustment. In conclusion, not being married, and more specifically, widowhood was more consistently associated with an increased risk of type 2 diabetes in men and this may be mediated, in part, through unfavorable changes in lifestyle, diet and adiposity.en
dc.language.isoen_USen
dc.publisherPublic Library of Scienceen
dc.relation.isversionofdoi:10.1371/journal.pone.0106720en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167705/pdf/en
dash.licenseLAAen_US
dc.subjectBiology and Life Sciencesen
dc.subjectPhysiologyen
dc.subjectPhysiological Parametersen
dc.subjectBody Weighten
dc.subjectObesityen
dc.subjectPsychologyen
dc.subjectHuman Relationsen
dc.subjectInterpersonal Relationshipsen
dc.subjectMedicine and Health Sciencesen
dc.subjectEpidemiologyen
dc.subjectSocial Epidemiologyen
dc.subjectMetabolic Disordersen
dc.subjectDiabetes Mellitusen
dc.subjectType 2 Diabetesen
dc.subjectType 2 Diabetes Risken
dc.subjectSocial Sciencesen
dc.titleBachelors, Divorcees, and Widowers: Does Marriage Protect Men from Type 2 Diabetes?en
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalPLoS ONEen
dash.depositing.authorCornelis, Marilyn C.en_US
dc.date.available2014-10-01T14:27:53Z
dash.hope.year2014en_US
dc.identifier.doi10.1371/journal.pone.0106720*
dash.contributor.affiliatedKubzansky, Laura
dash.contributor.affiliatedCornelis, Marilyn
dash.contributor.affiliatedTchetgen Tchetgen, Eric
dash.contributor.affiliatedChiuve, Stephanie
dash.contributor.affiliatedRimm, Eric
dash.contributor.affiliatedLiang, Liming
dash.contributor.affiliatedKawachi, Ichiro


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