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dc.contributor.authorWang, Dong D.en_US
dc.contributor.authorBakhotmah, Balkees A.en_US
dc.contributor.authorHu, Frank B.en_US
dc.contributor.authorAlzahrani, Hasan Alien_US
dc.date.accessioned2014-10-01T14:27:58Z
dc.date.issued2014en_US
dc.identifier.citationWang, Dong D., Balkees A. Bakhotmah, Frank B. Hu, and Hasan Ali Alzahrani. 2014. “Prevalence and Correlates of Diabetic Peripheral Neuropathy in a Saudi Arabic Population: A Cross-Sectional Study.” PLoS ONE 9 (9): e106935. doi:10.1371/journal.pone.0106935. http://dx.doi.org/10.1371/journal.pone.0106935.en
dc.identifier.issn1932-6203en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:12987260
dc.description.abstractThe purpose of this cross-sectional study was to investigate the prevalence and correlates of diabetic peripheral neuropathy (DPN) in a Saudi population. The study population consisted of 552 diabetic participants with an average age of 53.4 years. Among this population, 62.7% were male and 94.9% had type 2 diabetes. The average body mass index was 31.1 kg/m2. DPN was diagnosed based on a combination of reduced vibration perception measured by neurothesiometer and/or reduced light touch perception evaluated by the 10-g Semmes-Weinstein monofilament, as well as neurological symptoms. Information on socio-demographic variables, smoking status, duration of diabetes, and medications was obtained through interviews by physicians. Body weight, height, waist circumference, blood pressure and clinical markers were assessed following standard procedures. The prevalence of DPN in this population was 19.9% (95% CI, 16.7%-23.5%). In the multivariable analyses, longer duration of diabetes [odds ratio (OR) for every 5-year increase, 2.49, 95% CI, 1.75-3.53], abdominal obesity (OR, 2.53, 95% CI, 1.41-4.55), and higher levels of fasting blood glucose (OR for every 1 mmol/L increase, 1.05, 95% CI, 0.99-1.12), creatinine (OR for every 10 µmol/L increase, 1.07, 95% CI, 0.99-1.14) and white blood cell count (OR for every 106/L increase, 1.08, 95% CI, 1.01-1.16) were associated with higher odds of DPN, while oral hypoglycemic medication use was associated with a lower odds of DPN (OR, 0.47, 95% CI, 0.26-0.85). In this large Saudi population, several correlates for DPN, in addition to glycemic control and diabetes duration, were identified, including abdominal obesity, creatinine and white blood cell count.en
dc.language.isoen_USen
dc.publisherPublic Library of Scienceen
dc.relation.isversionofdoi:10.1371/journal.pone.0106935en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153691/pdf/en
dash.licenseLAAen_US
dc.subjectBiology and Life Sciencesen
dc.subjectAnatomyen
dc.subjectNervous Systemen
dc.subjectNutritionen
dc.subjectPhysiologyen
dc.subjectPhysiological Parametersen
dc.subjectBody Weighten
dc.subjectObesityen
dc.subjectMedicine and Health Sciencesen
dc.subjectCardiologyen
dc.subjectEndocrinologyen
dc.subjectDiabetic Endocrinologyen
dc.subjectEpidemiologyen
dc.subjectBiomarker Epidemiologyen
dc.subjectCardiovascular Disease Epidemiologyen
dc.subjectMetabolic Disordersen
dc.subjectDiabetes Mellitusen
dc.subjectType 1 Diabetesen
dc.subjectType 2 Diabetesen
dc.subjectNeurologyen
dc.subjectNeuromuscular Diseasesen
dc.subjectPublic and Occupational Healthen
dc.subjectGlobal Healthen
dc.subjectVascular Medicineen
dc.subjectVascular Diseasesen
dc.subjectPeripheral Vascular Diseaseen
dc.titlePrevalence and Correlates of Diabetic Peripheral Neuropathy in a Saudi Arabic Population: A Cross-Sectional Studyen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalPLoS ONEen
dash.depositing.authorHu, Frank B.en_US
dc.date.available2014-10-01T14:27:58Z
dc.identifier.doi10.1371/journal.pone.0106935*
dash.contributor.affiliatedHu, Frank


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