Show simple item record

dc.contributor.authorMehan, William A.en_US
dc.contributor.authorGonzález, R. Gilbertoen_US
dc.contributor.authorBuchbinder, Bradley R.en_US
dc.contributor.authorChen, John W.en_US
dc.contributor.authorCopen, William A.en_US
dc.contributor.authorGupta, Rajiven_US
dc.contributor.authorHirsch, Joshua A.en_US
dc.contributor.authorHunter, George J.en_US
dc.contributor.authorHunter, Scotten_US
dc.contributor.authorJohnson, Jason M.en_US
dc.contributor.authorKelly, Hillary R.en_US
dc.contributor.authorLarvie, Mykolen_US
dc.contributor.authorLev, Michael H.en_US
dc.contributor.authorPomerantz, Stuart R.en_US
dc.contributor.authorRapalino, Ottoen_US
dc.contributor.authorRincon, Sandraen_US
dc.contributor.authorRomero, Javier M.en_US
dc.contributor.authorSchaefer, Pamela W.en_US
dc.contributor.authorShah, Vinilen_US
dc.date.accessioned2014-11-03T17:40:18Z
dc.date.issued2014en_US
dc.identifier.citationMehan, W. A., R. G. González, B. R. Buchbinder, J. W. Chen, W. A. Copen, R. Gupta, J. A. Hirsch, et al. 2014. “Optimal Brain MRI Protocol for New Neurological Complaint.” PLoS ONE 9 (10): e110803. doi:10.1371/journal.pone.0110803. http://dx.doi.org/10.1371/journal.pone.0110803.en
dc.identifier.issn1932-6203en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:13347596
dc.description.abstractBackground/Purpose Patients with neurologic complaints are imaged with MRI protocols that may include many pulse sequences. It has not been documented which sequences are essential. We assessed the diagnostic accuracy of a limited number of sequences in patients with new neurologic complaints. Methods: 996 consecutive brain MRI studies from patients with new neurological complaints were divided into 2 groups. In group 1, reviewers used a 3-sequence set that included sagittal T1-weighted, axial T2-weighted fluid-attenuated inversion recovery, and axial diffusion-weighted images. Subsequently, another group of studies were reviewed using axial susceptibility-weighted images in addition to the 3 sequences. The reference standard was the study's official report. Discrepancies between the limited sequence review and the reference standard including Level I findings (that may require immediate change in patient management) were identified. Results: There were 84 major findings in 497 studies in group 1 with 21 not identified in the limited sequence evaluations: 12 enhancing lesions and 3 vascular abnormalities identified on MR angiography. The 3-sequence set did not reveal microhemorrhagic foci in 15 of 19 studies. There were 117 major findings in 499 studies in group 2 with 19 not identified on the 4-sequence set: 17 enhancing lesions and 2 vascular lesions identified on angiography. All 87 Level I findings were identified using limited sequence (56 acute infarcts, 16 hemorrhages, and 15 mass lesions). Conclusion: A 4-pulse sequence brain MRI study is sufficient to evaluate patients with a new neurological complaint except when contrast or angiography is indicated.en
dc.language.isoen_USen
dc.publisherPublic Library of Scienceen
dc.relation.isversionofdoi:10.1371/journal.pone.0110803en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208779/pdf/en
dash.licenseLAAen_US
dc.subjectMedicine and Health Sciencesen
dc.subjectDiagnostic Medicineen
dc.subjectDiagnostic Radiologyen
dc.subjectMagnetic Resonance Imagingen
dc.subjectRadiology and Imagingen
dc.titleOptimal Brain MRI Protocol for New Neurological Complainten
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalPLoS ONEen
dash.depositing.authorMehan, William A.en_US
dc.date.available2014-11-03T17:40:18Z
dc.identifier.doi10.1371/journal.pone.0110803*
dash.authorsorderedfalse
dash.contributor.affiliatedRincon, Sandra
dash.contributor.affiliatedMehan, William
dash.contributor.affiliatedHunter, George
dash.contributor.affiliatedRapalino, Otto
dash.contributor.affiliatedBuchbinder, Bradley
dash.contributor.affiliatedCopen, William
dash.contributor.affiliatedGupta, Rajiv
dash.contributor.affiliatedLarvie, Mykol
dash.contributor.affiliatedHirsch, Joshua
dash.contributor.affiliatedSchaefer, Pamela
dash.contributor.affiliatedRomero, Javier
dash.contributor.affiliatedPomerantz, Stuart
dash.contributor.affiliatedLev, Michael
dash.contributor.affiliatedChen, John


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record