Show simple item record

dc.contributor.authorSchultze, Tilmanen_US
dc.contributor.authorIzar, Benjaminen_US
dc.contributor.authorQing, Xiaoxingen_US
dc.contributor.authorMannala, Gopala K.en_US
dc.contributor.authorHain, Torstenen_US
dc.date.accessioned2014-11-03T17:40:50Z
dc.date.issued2014en_US
dc.identifier.citationSchultze, Tilman, Benjamin Izar, Xiaoxing Qing, Gopala K. Mannala, and Torsten Hain. 2014. “Current status of antisense RNA-mediated gene regulation in Listeria monocytogenes.” Frontiers in Cellular and Infection Microbiology 4 (1): 135. doi:10.3389/fcimb.2014.00135. http://dx.doi.org/10.3389/fcimb.2014.00135.en
dc.identifier.issn2235-2988en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:13347660
dc.description.abstractListeria monocytogenes is a Gram-positive human-pathogen bacterium that served as an experimental model for investigating fundamental processes of adaptive immunity and virulence. Recent novel technologies allowed the identification of several hundred non-coding RNAs (ncRNAs) in the Listeria genome and provided insight into an unexpected complex transcriptional machinery. In this review, we discuss ncRNAs that are encoded on the opposite strand of the target gene and are therefore termed antisense RNAs (asRNAs). We highlight mechanistic and functional concepts of asRNAs in L. monocytogenes and put these in context of asRNAs in other bacteria. Understanding asRNAs will further broaden our knowledge of RNA-mediated gene regulation and may provide targets for diagnostic and antimicrobial development.en
dc.language.isoen_USen
dc.publisherFrontiers Media S.A.en
dc.relation.isversionofdoi:10.3389/fcimb.2014.00135en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179725/pdf/en
dash.licenseLAAen_US
dc.subjectMini Review Articleen
dc.subjecten
dc.subjectantisense RNAen
dc.subjectasRNAen
dc.subjectregulationen
dc.subjectnext generation sequencingen
dc.subjectbacteriaen
dc.titleCurrent status of antisense RNA-mediated gene regulation in Listeria monocytogenesen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalFrontiers in Cellular and Infection Microbiologyen
dash.depositing.authorIzar, Benjaminen_US
dc.date.available2014-11-03T17:40:50Z
dc.identifier.doi10.3389/fcimb.2014.00135*
dash.contributor.affiliatedIzar, Benjamin


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record