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Hyperinsulinemia Dietary and Lifestyle Scores and Cancer Risk
(2017-04-28)
Hyperinsulinemia is a risk factor for several cancers, broadly speaking digestive system cancers and potentially prostate cancer. My colleagues and I developed hyperinsulinemia dietary and lifestyle scores in the Nurses’ ...
Barriers and Opportunities for Cardiovascular Disease Prevention in Low- and High-Income Countries
(2017-05-01)
Cardiovascular disease is the leading cause of death worldwide and hypertension is the leading modifiable risk factor for death. Global studies have shown a high prevalence of hypertension in East Africa, but the reasons ...
Evaluating Approaches With the Potential to Improve Health Outcomes While Reducing Unnecessary Interventions in Infectious Disease Public Health
(2019-09-24)
We are increasingly tasked with improving value in healthcare. We wish to do more with less. More specifically, we aim to simultaneously improve health outcomes while reducing resource utilization, including unnecessary ...
Optimizing Interventions to Control Emerging Infectious Diseases
(2017-03-29)
Inherent uncertainties surrounding emerging and re-emerging infectious diseases pose unique challenges to control efforts. Concurrent with the acceleration of disease emergence in recent decades, advances in modern ...
Air Pollution in Relation to Mammographic Density, Breast Cancer Survival, and Breast Tissue Gene Expression
(2017-04-24)
Ambient air pollution and particulate matter (PM) are Group 1 human carcinogens and induce systemic effects relevant to carcinogenesis. Breast cancer is the most diagnosed cancer, excluding non-melanoma skin cancer, and ...
Neighborhood Greenness and Prostate Cancer: Association and Explanation in Diverse Populations
(2020-01-27)
Prostate cancer (CaP) is the most common non-cutaneous cancer diagnosed among men in the United States. Neighborhood greenness could confer benefits to men at risk of CaP by promoting healthy lifestyles and reducing ...
Statistical Analysis and Methods for Human -Omics Data
(2017-04-18)
Fast advancement in high-throughput technology has allowed screening of millions of molecular markers at multiple levels of the biological system in large samples to study the genetic basis and biological variation underlying ...
Predicted Lean Body Mass and Fat Mass: Novel Insights Into Obesity, Chronic Disease, and Mortality Research
(2017-04-25)
Body mass index (BMI) is widely used measure of overall adiposity in epidemiological studies. However, BMI has a critical limitation that it cannot distinguish different body compartments, and therefore fails to capture ...
Polygenic Score to Understand Cancer Etiology and Predict Cancer Risks
(2020-04-29)
Genetics have been an important risk factor for cancer. The information we learned from genome-wide association studies (GWAS) provide researchers with tools and new approach to better understand cancer epidemiology. In ...
Lifestyle, Genetics, and Their Interactions in Determining Parkinson’s Disease Risk
(2017-04-19)
Parkinson’s disease is the second most common neurodegenerative disease, afflicting 1-2% of the population over the age of 65, and its prevalence is expected to rise as the population of older adults increases, highlighting ...