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Neurological Soft Signs, Cognition in Childhood, Attention Deficit Hyperactivity Disorder and Lifetime Major Depressive Disorder
(2017-01-11)
Background: Neurological soft signs (NSS), subtle but abnormal motor and sensory signs and involuntary movements, have been implicated as risk factors for a number of psychiatric and neurodevelopmental disorders. Prior ...
Comparative Safety of Antiretroviral Drugs to Treat HIV During Pregnancy
(2017-01-23)
Each year, nearly 1.5 million women with HIV become pregnant, and require antiretroviral treatment to reduce risk of perinatal transmission of the virus and improve their own health. The safety of currently approved ...
Summary Score-Based Confounding Control in Studies of New Drugs
(2017-09-21)
Epidemiological studies of newly marketed drugs are often undertaken to assess questions of safety and effectiveness that did not arise during a drug’s pre-approval studies. However, unlike in randomized controlled trials, ...
Effect of Smoking Cessation and Other Lifestyle Modifications on Weight Gain and Risk of Stroke: An Application of the Parametric G-Formula
(2017-09-26)
Developing public health policies for chronic disease prevention requires estimating the effects of long-term lifestyle interventions. In the absence of randomized trials conducted over long periods of time, the parametric ...
Maternal Diet, Arsenic Exposure, and Pregnancy Outcomes in Bangladesh
(2017-09-06)
This study investigated the relationship between maternal diet, arsenic exposure and birth outcomes in the Bangladeshi administrative regions of Sirajdikhan and Pabna Sadar. First, the study assessed the validity of a ...
Long-Term Use of Cardiovascular Medications: Identifying and Encouraging Optimal Duration
(2017-09-20)
In the face of increasingly widespread availability and uptake of medications to treat and prevent cardiovascular disease, this dissertation is motivated by two broad research questions regarding the duration of cardiovascular ...
Social Support and Older Adult Health in China
(2017-09-22)
Social support refers to the provision of support through the real or perceived existence of resources in social relationships, which is one of the main mechanisms through which social networks may influence health outcomes. ...
Prenatal Arsenic Exposure and Birth Outcomes in a Longitudinal Birth Cohort in Bangladesh
(2017-04-25)
This research provides an in-depth investigation into the associations between prenatal arsenic exposure and adverse birth outcomes with a view to mechanistically explain these associations by exploring miRNA expression ...