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dc.contributor.authorChen, Muen_US
dc.contributor.authorSun, Qien_US
dc.contributor.authorGiovannucci, Edwarden_US
dc.contributor.authorMozaffarian, Dariushen_US
dc.contributor.authorManson, JoAnn Een_US
dc.contributor.authorWillett, Walter Cen_US
dc.contributor.authorHu, Frank Ben_US
dc.date.accessioned2014-12-02T21:27:25Z
dc.date.issued2014en_US
dc.identifier.citationChen, Mu, Qi Sun, Edward Giovannucci, Dariush Mozaffarian, JoAnn E Manson, Walter C Willett, and Frank B Hu. 2014. “Dairy consumption and risk of type 2 diabetes: 3 cohorts of US adults and an updated meta-analysis.” BMC Medicine 12 (1): 215. doi:10.1186/s12916-014-0215-1. http://dx.doi.org/10.1186/s12916-014-0215-1.en
dc.identifier.issn1741-7015en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:13454648
dc.description.abstractBackground: The relation between consumption of different types of dairy and risk of type 2 diabetes (T2D) remains uncertain. Therefore, we aimed to evaluate the association between total dairy and individual types of dairy consumptions and incident T2D in US adults. Methods: We followed 41,436 men in the Health Professionals Follow-Up Study (1986 to 2010), 67,138 women in the Nurses’ Health Study (1980 to 2010), and 85,884 women in the Nurses’ Health Study II (1991 to 2009). Diet was assessed by validated food-frequency questionnaires, and data were updated every four years. Incident T2D was confirmed by a validated supplementary questionnaire. Results: During 3,984,203 person-years of follow-up, we documented 15,156 incident T2D cases. After adjustment for age, body mass index (BMI) and other lifestyle and dietary risk factors, total dairy consumption was not associated with T2D risk and the pooled hazard ratio (HR) (95% confidence interval (CI)) of T2D for one serving/day increase in total dairy was 0.99 (0.98, 1.01). Among different types of dairy products, neither low-fat nor high-fat dairy intake was appreciably associated with risk of T2D. However, yogurt intake was consistently and inversely associated with T2D risk across the three cohorts with the pooled HR of 0.83 (0.75, 0.92) for one serving/day increment (P for trend <0.001). We conducted a meta-analysis of 14 prospective cohorts with 459,790 participants and 35,863 incident T2D cases; the pooled relative risks (RRs) (95% CIs) were 0.98 (0.96, 1.01) and 0.82 (0.70, 0.96) for one serving total dairy/day and one serving yogurt/day, respectively. Conclusions: Higher intake of yogurt is associated with a reduced risk of T2D, whereas other dairy foods and consumption of total dairy are not appreciably associated with incidence of T2D. Electronic supplementary material The online version of this article (doi:10.1186/s12916-014-0215-1) contains supplementary material, which is available to authorized users.en
dc.language.isoen_USen
dc.publisherBioMed Centralen
dc.relation.isversionofdoi:10.1186/s12916-014-0215-1en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243376/pdf/en
dash.licenseLAAen_US
dc.subjectdairyen
dc.subjecttype 2 diabetesen
dc.subjectcohorten
dc.subjectmeta-analysisen
dc.titleDairy consumption and risk of type 2 diabetes: 3 cohorts of US adults and an updated meta-analysisen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalBMC Medicineen
dash.depositing.authorChen, Muen_US
dc.date.available2014-12-02T21:27:25Z
dc.identifier.doi10.1186/s12916-014-0215-1*
dash.contributor.affiliatedSun, Qi
dash.contributor.affiliatedChen, Mu
dash.contributor.affiliatedManson, JoAnn
dash.contributor.affiliatedHu, Frank
dash.contributor.affiliatedWillett, Walter
dash.contributor.affiliatedGiovannucci, Edward


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