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dc.contributor.authorKaddumukasa, Marken_US
dc.contributor.authorBuwembo, Williamen_US
dc.contributor.authorSekikubo, Musaen_US
dc.contributor.authorNaiwumbwe, Halimaen_US
dc.contributor.authorNamusoke, Fatumaen_US
dc.contributor.authorKiwuwa, Stephenen_US
dc.contributor.authorOketch, Brendaen_US
dc.contributor.authorNoor, Ramadhanien_US
dc.contributor.authorChilengi, Romaen_US
dc.contributor.authorMworozi, Edisonen_US
dc.contributor.authorKironde, Freden_US
dc.date.accessioned2014-12-02T21:27:42Z
dc.date.issued2014en_US
dc.identifier.citationKaddumukasa, M., W. Buwembo, M. Sekikubo, H. Naiwumbwe, F. Namusoke, S. Kiwuwa, B. Oketch, et al. 2014. “Malariometric indices from Iganga, Uganda: baseline characterization in preparation of GMZ2 vaccine trial.” BMC Research Notes 7 (1): 793. doi:10.1186/1756-0500-7-793. http://dx.doi.org/10.1186/1756-0500-7-793.en
dc.identifier.issn1756-0500en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:13454672
dc.description.abstractBackground: Malaria still remains the leading cause of childhood morbidity and mortality in Uganda. Interventions like malaria vaccines which reduce the malaria burden are needed in malaria endemic communities. There is need to establish baseline characteristics in vaccine trial study sites. This study determined the following baseline malariometric indices: spleen rates, bed net use, malaria parasitaemia and malaria episodes in an inception cohort of children aged 12 – 60 months in Iganga district, Uganda. Methods: In a longitudinal cohort study, 748 children were enrolled with 397 in an active follow up arm and 351 in a passive arm. The children in the two arms were followed for 6 months to determine the incidence of malaria episodes. Results: The overall baseline spleen rate was 8.2% (61/748) among the study participants. Of the households surveyed, about 36% reported using bed nets and almost 30% of the users had insecticide-treated nets. 274 (36.6%) of the study participants had a history of fever in the past 24 hrs at the time of the baseline survey. All participants had a peripheral blood smear for malaria parasites done at enrollment with 76.8% having the asexual form of malaria parasites. The malaria episodes per child per year were 1.5 and 0.79 in the active and passive follow up arms respectively. Conclusions: There is a high prevalence of malaria asexual parasitaemia in children below five years. The bed net usage still remains low among this population. These baseline malariometric indices have important implication for malaria control interventions.en
dc.language.isoen_USen
dc.publisherBioMed Centralen
dc.relation.isversionofdoi:10.1186/1756-0500-7-793en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232662/pdf/en
dash.licenseLAAen_US
dc.subjectMalaria episodesen
dc.subjectParasitaemiaen
dc.subjectSurveillanceen
dc.subjectIgangaen
dc.subjectUgandaen
dc.titleMalariometric indices from Iganga, Uganda: baseline characterization in preparation of GMZ2 vaccine trialen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalBMC Research Notesen
dc.date.available2014-12-02T21:27:42Z
dc.identifier.doi10.1186/1756-0500-7-793*
dash.authorsorderedfalse


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