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dc.contributor.authorRoujol, Sébastienen_US
dc.contributor.authorFoppa, Muriloen_US
dc.contributor.authorBasha, Tamer Aen_US
dc.contributor.authorAkçakaya, Mehmeten_US
dc.contributor.authorKissinger, Kraig Ven_US
dc.contributor.authorGoddu, Bethen_US
dc.contributor.authorBerg, Sophieen_US
dc.contributor.authorNezafat, Rezaen_US
dc.date.accessioned2014-12-02T21:28:57Z
dc.date.issued2014en_US
dc.identifier.citationRoujol, Sébastien, Murilo Foppa, Tamer A Basha, Mehmet Akçakaya, Kraig V Kissinger, Beth Goddu, Sophie Berg, and Reza Nezafat. 2014. “Accelerated free breathing ECG triggered contrast enhanced pulmonary vein magnetic resonance angiography using compressed sensing.” Journal of Cardiovascular Magnetic Resonance 16 (1): 91. doi:10.1186/s12968-014-0091-z. http://dx.doi.org/10.1186/s12968-014-0091-z.en
dc.identifier.issn1097-6647en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:13454801
dc.description.abstractBackground: To investigate the feasibility of accelerated electrocardiogram (ECG)-triggered contrast enhanced pulmonary vein magnetic resonance angiography (CE-PV MRA) with isotropic spatial resolution using compressed sensing (CS). Methods: Nineteen patients (59 ± 13 y, 11 M) referred for MR were scanned using the proposed accelerated free breathing ECG-triggered 3D CE-PV MRA sequence (FOV = 340 × 340 × 110 mm3, spatial resolution = 1.5 × 1.5 × 1.5 mm3, acquisition window = 140 ms at mid diastole and CS acceleration factor = 5) and a conventional first-pass breath-hold non ECG-triggered 3D CE-PV MRA sequence. CS data were reconstructed offline using low-dimensional-structure self-learning and thresholding reconstruction (LOST) CS reconstruction. Quantitative analysis of PV sharpness and subjective qualitative analysis of overall image quality were performed using a 4-point scale (1: poor; 4: excellent). Results: Quantitative PV sharpness was increased using the proposed approach (0.73 ± 0.09 vs. 0.51 ± 0.07 for the conventional CE-PV MRA protocol, p < 0.001). There were no significant differences in the subjective image quality scores between the techniques (3.32 ± 0.94 vs. 3.53 ± 0.77 using the proposed technique). Conclusions: CS-accelerated free-breathing ECG-triggered CE-PV MRA allows evaluation of PV anatomy with improved sharpness compared to conventional non-ECG gated first-pass CE-PV MRA. This technique may be a valuable alternative for patients in which the first pass CE-PV MRA fails due to inaccurate first pass timing or inability of the patient to perform a 20–25 seconds breath-hold.en
dc.language.isoen_USen
dc.publisherBioMed Centralen
dc.relation.isversionofdoi:10.1186/s12968-014-0091-zen
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240816/pdf/en
dash.licenseLAAen_US
dc.subjectMagnetic resonance angiographyen
dc.subjectPulmonary veinen
dc.subject3D acquisitionen
dc.subjectAcceleration techniquesen
dc.subjectCompressed sensingen
dc.titleAccelerated free breathing ECG triggered contrast enhanced pulmonary vein magnetic resonance angiography using compressed sensingen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalJournal of Cardiovascular Magnetic Resonanceen
dash.depositing.authorRoujol, Sébastienen_US
dc.date.available2014-12-02T21:28:57Z
dc.identifier.doi10.1186/s12968-014-0091-z*
dash.contributor.affiliatedRoujol, Sébastien
dash.contributor.affiliatedBasha, Tamer A
dash.contributor.affiliatedNezafat, Reza
dash.contributor.affiliatedAkcakaya, Mehmet


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