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dc.contributor.authorLee, Mihyeen_US
dc.contributor.authorNordio, Francescoen_US
dc.contributor.authorZanobetti, Antonellaen_US
dc.contributor.authorKinney, Patricken_US
dc.contributor.authorVautard, Roberten_US
dc.contributor.authorSchwartz, Joelen_US
dc.date.accessioned2015-01-05T18:26:31Z
dc.date.issued2014en_US
dc.identifier.citationLee, Mihye, Francesco Nordio, Antonella Zanobetti, Patrick Kinney, Robert Vautard, and Joel Schwartz. 2014. “Acclimatization across space and time in the effects of temperature on mortality: a time-series analysis.” Environmental Health 13 (1): 89. doi:10.1186/1476-069X-13-89. http://dx.doi.org/10.1186/1476-069X-13-89.en
dc.identifier.issn1476-069Xen
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:13581056
dc.description.abstractBackground: Climate change has increased the days of unseasonal temperature. Although many studies have examined the association between temperature and mortality, few have examined the timing of exposure where whether this association varies depending on the exposure month even at the same temperature. Therefore, we investigated monthly differences in the effects of temperature on mortality in a study comprising a wide range of weather and years, and we also investigated heterogeneity among regions. Methods: We analyzed 38,005,616 deaths from 148 cities in the U.S. from 1973 through 2006. We fit city specific Poisson regressions to examine the effect of temperature on mortality separately for each month of the year, using penalized splines. We used cluster analysis to group cities with similar weather patterns, and combined results across cities within clusters using meta-smoothing. Results: There was substantial variation in the effects of the same temperature by month. Heat effects were larger in the spring and early summer and cold effects were larger in late fall. In addition, heat effects were larger in clusters where high temperatures were less common, and vice versa for cold effects. Conclusions: The effects of a given temperature on mortality vary spatially and temporally based on how unusual it is for that time and location. This suggests changes in variability of temperature may be more important for health as climate changes than changes of mean temperature. More emphasis should be placed on warnings targeted to early heat/cold temperature for the season or month rather than focusing only on the extremes. Electronic supplementary material The online version of this article (doi:10.1186/1476-069X-13-89) contains supplementary material, which is available to authorized users.en
dc.language.isoen_USen
dc.publisherBioMed Centralen
dc.relation.isversionofdoi:10.1186/1476-069X-13-89en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271464/pdf/en
dash.licenseLAAen_US
dc.subjectTemperature and mortalityen
dc.subjectAcclimationen
dc.subjectAcclimatizationen
dc.subjectClimate changeen
dc.subjectGlobal warmingen
dc.titleAcclimatization across space and time in the effects of temperature on mortality: a time-series analysisen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalEnvironmental Healthen
dash.depositing.authorLee, Mihyeen_US
dc.date.available2015-01-05T18:26:31Z
dc.identifier.doi10.1186/1476-069X-13-89*
dash.contributor.affiliatedLee, Mihye
dash.contributor.affiliatedZanobetti, Antonella
dash.contributor.affiliatedSchwartz, Joel


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