Show simple item record

dc.contributor.authorSrihari, Vinod Hen_US
dc.contributor.authorTek, Cenken_US
dc.contributor.authorPollard, Jessicaen_US
dc.contributor.authorZimmet, Suzannahen_US
dc.contributor.authorKeat, Janeen_US
dc.contributor.authorCahill, John Den_US
dc.contributor.authorKucukgoncu, Suaten_US
dc.contributor.authorWalsh, Barbara Cen_US
dc.contributor.authorLi, Fangyongen_US
dc.contributor.authorGueorguieva, Ralitzaen_US
dc.contributor.authorLevine, Ninaen_US
dc.contributor.authorMesholam-Gately, Raquelle Ien_US
dc.contributor.authorFriedman-Yakoobian, Michelleen_US
dc.contributor.authorSeidman, Larry Jen_US
dc.contributor.authorKeshavan, Matcheri Sen_US
dc.contributor.authorMcGlashan, Thomas Hen_US
dc.contributor.authorWoods, Scott Wen_US
dc.date.accessioned2015-01-05T18:27:57Z
dc.date.issued2014en_US
dc.identifier.citationSrihari, V. H., C. Tek, J. Pollard, S. Zimmet, J. Keat, J. D. Cahill, S. Kucukgoncu, et al. 2014. “Reducing the duration of untreated psychosis and its impact in the U.S.: the STEP-ED study.” BMC Psychiatry 14 (1): 335. doi:10.1186/s12888-014-0335-3. http://dx.doi.org/10.1186/s12888-014-0335-3.en
dc.identifier.issn1471-244Xen
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:13581182
dc.description.abstractBackground: Early intervention services for psychotic disorders optimally interlock strategies to deliver: (i) Early Detection (ED) to shorten the time between onset of psychotic symptoms and effective treatment (i.e. Duration of Untreated Psychosis, DUP); and (ii) comprehensive intervention during the subsequent 2 to 5 years. In the latter category, are teams (‘First-episode Services’ or FES) that integrate several empirically supported treatments and adapt their delivery to younger patients and caregivers. There is an urgent need to hasten access to established FES in the U.S. Despite improved outcomes for those in treatment, these FES routinely engage patients a year or more after psychosis onset. The Scandinavian TIPS study was able to effectively reduce DUP in a defined geographic catchment. The guiding questions for this study are: can a U.S. adaptation of the TIPS approach to ED substantially reduce DUP and improve outcomes beyond existing FES? Methods/Design The primary aim is to determine whether ED can reduce DUP in the US, as compared to usual detection. ED will be implemented by one FES (STEP) based in southern Connecticut, and usual detection efforts will continue at a comparable FES (PREPR) serving the greater Boston metropolitan area. The secondary aim is to determine whether DUP reduction can improve presentation, engagement and early outcomes in FES care. A quasi-experimental design will compare the impact of ED on DUP at STEP compared to PREPR over 3 successive campaign years. The campaign will deploy 3 components that seek to transform pathways to care in 8 towns surrounding STEP. Social marketing approaches will inform a public education campaign to enable rapid and effective help-seeking behavior. Professional outreach and detailing to a wide variety of care providers, including those in the healthcare, educational and judicial sectors, will facilitate rapid redirection of appropriate patients to STEP. Finally, performance improvement measures within STEP will hasten engagement upon referral. Discussion STEP-ED will test an ED campaign adapted to heterogeneous U.S. pathways to care while also improving our understanding of these pathways and their impact on early outcomes. Trial registration ClinicalTrials.gov: NCT02069925. Registered 20 February 2014.en
dc.language.isoen_USen
dc.publisherBioMed Centralen
dc.relation.isversionofdoi:10.1186/s12888-014-0335-3en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262386/pdf/en
dash.licenseLAAen_US
dc.subjectEarly interventionen
dc.subjectFirst-episode servicesen
dc.subjectDuration of untreated psychosisen
dc.subjectSchizophreniaen
dc.subjectFirst-episode psychosisen
dc.subjectPublic health campaignsen
dc.subjectHealth communication campaignsen
dc.titleReducing the duration of untreated psychosis and its impact in the U.S.: the STEP-ED studyen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalBMC Psychiatryen
dash.depositing.authorMesholam-Gately, Raquelle Ien_US
dc.date.available2015-01-05T18:27:57Z
dc.identifier.doi10.1186/s12888-014-0335-3*
dash.authorsorderedfalse
dash.contributor.affiliatedSeidman, Larry Joel
dash.contributor.affiliatedKeshavan, Matcheri
dash.contributor.affiliatedFriedman-Yakoobian, Michelle
dash.contributor.affiliatedMesholam-Gately, Raquelle


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record