Hearty miR-363 controls HAND1 in cardiac cell specification

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Hearty miR-363 controls HAND1 in cardiac cell specification

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Title: Hearty miR-363 controls HAND1 in cardiac cell specification
Author: Gupta, Manoj K; Rao, Tata Nageswara

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Citation: Gupta, Manoj K., and Tata Nageswara Rao. 2014. “Hearty miR-363 controls HAND1 in cardiac cell specification.” Stem Cell Research & Therapy 5 (4): 89. doi:10.1186/scrt478. http://dx.doi.org/10.1186/scrt478.
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Abstract: MicroRNAs regulate target gene expression post-transcriptionally in a myriad of cell types and play critical roles in diverse physiological and pathological processes, including cardiomyocyte development, differentiation, and regeneration. The recent publication in Stem Cell Research and Therapy by Wagh and colleagues reports a novel regulatory role for miR-363 in cardiomyocyte specification. By employing microRNA expression profiling and functional knockdown studies on human embryonic stem cell-derived cardiomyocytes, the authors identified miR-363 as an upstream negative regulator of left ventricular specification transcription factor HAND1.
Published Version: doi:10.1186/scrt478
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282149/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:13890805
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