Gibbon genome and the fast karyotype evolution of small apes
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Author
Carbone, Lucia
Harris, R. Alan
Gnerre, Sante
Veeramah, Krishna R.
Lorente-Galdos, Belen
Huddleston, John
Meyer, Thomas J.
Herrero, Javier
Roos, Christian
Aken, Bronwen
Anaclerio, Fabio
Archidiacono, Nicoletta
Baker, Carl
Barrell, Daniel
Batzer, Mark A.
Beal, Kathryn
Blancher, Antoine
Bohrson, Craig L.
Brameier, Markus
Campbell, Michael S.
Capozzi, Oronzo
Casola, Claudio
Chiatante, Giorgia
Cree, Andrew
Damert, Annette
de Jong, Pieter J.
Dumas, Laura
Fernandez-Callejo, Marcos
Flicek, Paul
Fuchs, Nina V.
Gut, Marta
Gut, Ivo
Hahn, Matthew W.
Hernandez-Rodriguez, Jessica
Hillier, LaDeana W.
Hubley, Robert
Ianc, Bianca
Izsvák, Zsuzsanna
Jablonski, Nina G.
Johnstone, Laurel M.
Karimpour-Fard, Anis
Konkel, Miriam K.
Kostka, Dennis
Lazar, Nathan H.
Lee, Sandra L.
Lewis, Lora R.
Liu, Yue
Locke, Devin P.
Mendez, Fernando L.
Muffato, Matthieu
Nazareth, Lynne V.
Nevonen, Kimberly A.
O,Bleness, Majesta
Ochis, Cornelia
Odom, Duncan T.
Pollard, Katherine S.
Quilez, Javier
Rocchi, Mariano
Schumann, Gerald G.
Searle, Stephen
Sikela, James M.
Skollar, Gabriella
Smit, Arian
Sonmez, Kemal
Hallers, Boudewijn ten
Terhune, Elizabeth
Thomas, Gregg W.C.
Ullmer, Brygg
Ventura, Mario
Walker, Jerilyn A.
Wall, Jeffrey D.
Walter, Lutz
Ward, Michelle C.
Wheelan, Sarah J.
Whelan, Christopher W.
White, Simon
Wilhelm, Larry J.
Woerner, August E.
Yandell, Mark
Zhu, Baoli
Hammer, Michael F.
Marques-Bonet, Tomas
Eichler, Evan E.
Fulton, Lucinda
Fronick, Catrina
Muzny, Donna M.
Warren, Wesley C.
Worley, Kim C.
Rogers, Jeffrey
Wilson, Richard K.
Gibbs, Richard A.
Note: Order does not necessarily reflect citation order of authors.
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https://doi.org/10.1038/nature13679Metadata
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Carbone, L., R. A. Harris, S. Gnerre, K. R. Veeramah, B. Lorente-Galdos, J. Huddleston, T. J. Meyer, et al. 2014. “Gibbon genome and the fast karyotype evolution of small apes.” Nature 513 (7517): 195-201. doi:10.1038/nature13679. http://dx.doi.org/10.1038/nature13679.Abstract
Gibbons are small arboreal apes that display an accelerated rate of evolutionary chromosomal rearrangement and occupy a key node in the primate phylogeny between Old World monkeys and great apes. Here we present the assembly and analysis of a northern white-cheeked gibbon (Nomascus leucogenys) genome. We describe the propensity for a gibbon-specific retrotransposon (LAVA) to insert into chromosome segregation genes and alter transcription by providing a premature termination site, suggesting a possible molecular mechanism for the genome plasticity of the gibbon lineage. We further show that the gibbon genera (Nomascus, Hylobates, Hoolock and Symphalangus) experienced a near-instantaneous radiation ~5 million years ago, coincident with major geographical changes in Southeast Asia that caused cycles of habitat compression and expansion. Finally, we identify signatures of positive selection in genes important for forelimb development (TBX5) and connective tissues (COL1A1) that may have been involved in the adaptation of gibbons to their arboreal habitat.Other Sources
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249732/pdf/Terms of Use
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http://nrs.harvard.edu/urn-3:HUL.InstRepos:14351042
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