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dc.contributor.authorYablonka, Adi
dc.contributor.authorSobel, Noam
dc.contributor.authorHaddad, Rafi
dc.date.accessioned2015-04-21T19:25:04Z
dc.date.issued2012
dc.identifier.citationYablonka, A., N. Sobel, and R. Haddad. 2012. “Odorant Similarity in the Mouse Olfactory Bulb.” Proceedings of the National Academy of Sciences 109 (43) (August 22): E2916–E2917. doi:10.1073/pnas.1211623109.en_US
dc.identifier.issn0027-8424en_US
dc.identifier.issn1091-6490en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:14549988
dc.description.abstractIt is widely held that odorant chemical features are mapped onto the olfactory epithelium (1, 2) and bulb (3), such that similar odorants activate common receptors and glomeruli. After applying ultra-high-resolution calcium-indicator dependent imaging to the olfactory bulb, Ma et al. (4) failed to identify a correlation between odorant pairwise structural differences and pairwise neuronal response differences [figure 4E in Ma et al. (4)]. They concluded that, “response similarity was not dictated by structural similarity of the odors, and vice versa.” Ma et al. made their raw data available for download, allowing us to identify several analysis decisions that may underlie their null result. First, Ma et al. did not normalize the values of the various physicochemical descriptors. These measurements use …en_US
dc.description.sponsorshipMolecular and Cellular Biologyen_US
dc.language.isoen_USen_US
dc.publisherProceedings of the National Academy of Sciencesen_US
dc.relation.isversionofdoi:10.1073/pnas.1211623109en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491526/en_US
dash.licenseLAA
dc.titleOdorant similarity in the mouse olfactory bulben_US
dc.typeJournal Articleen_US
dc.description.versionAccepted Manuscripten_US
dc.relation.journalProceedings of the National Academy of Sciencesen_US
dc.date.available2015-04-21T19:25:04Z
dc.identifier.doi10.1073/pnas.1211623109*


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