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The Relationship Between Extracellular Free-Water and Gray Matter Volume in Retired Professional Football Players With History of Mild Repetitive Head Injuries
(2017-02-25)
The goal of this work was to investigate whether there was a relationship present between extracellular free water and gray matter volumes in the brains of retired professional football players. A study done by Maier-Hein ...
Rapid Response, High-Throughput Extraction of Biosafety Level 4 Viral Nucleic Acids
(2017-09-13)
Recent outbreaks of Ebola and Lassa virus have highlighted the need for real-time monitoring of virus evolution and spread using genome sequencing to enable rapid response efforts. For these category A pathogens, this ...
A Poly (Lactic Co Glycolic) Acid Based Dry Powder Inhaler for the Treatment of Pulmonary Tuberculosis
(2017-11-13)
The goal of this paper was to investigate the feasibility of a novel Poly (Lactic Co Glycolic) Acid (PLGA) based Dry Powder Inhaler in the treatment of pulmonary tuberculosis. First line TB drugs are highly effective in ...
IgA Antibody Responses to Borrelia Burgdorferi and Three Specific Autoantigens in Patients With Lyme Disease: Correlations With Cytokine Mediators and Disease Duration
(2017-05-13)
The aim of this research was to investigate IgA antibody responses to Borrelia burgdorferi and 3 related autoantigens in patients with early manifestations of Lyme disease, including those with erythema migrans (EM) and ...
How Bluegill Sunfish Maneuver: Analysis of Body and Fin Motion Under a Horizontal Obstacle
(2017-10-31)
This study investigates how bluegill sunfish control fin motion to deal with the added locomotor complexity of swimming under a horizontal obstacle. While previous studies have focused on upright swimming in the forward ...
Mitigating the Unmet Needs of Hemophilia Patients: A Case Study of the Development Strategy Behind a Novel siRNA Hemophilia Combination Medical Device.
(2017-10-24)
The purpose of this case study is to discuss the strategy behind the selection and development of a novel combination medical device to treat hemophilia patients in order to improve treatment for all segments of the ...
The Role of Chemokines CCL19b and CCL25b in T Cell Recruitment Into Melanoma Tumors.
(2017-08-24)
Malignant melanoma is an extremely metastatic cancer that is highly resistant to conventional therapy. One of the developing approaches to address melanoma involves immunotherapy. Immunotherapy involves harnessing the ...
An Analysis of the SmartCells Business Model and Its General Applicability Toward Building Successful Early-Stage Ventures in the Pharmaceutical Industry
(2017-03-29)
SmartCells developed a technology that would re-engineer the existing pharmaceutical, insulin, to perform in a way that was safer and more efficacious than the original underlying drug (Zion, 2004). This novel approach ...
Exploring the Use of Desktop 3D Printing for Microfluidics Prototyping
(2017-04-07)
Despite the tremendous impact of 3D printing on mechanical and design prototypes the use of 3D printers in microfluidics has been extremely limited. The current methods of constructing microfluidic devices use relatively ...
Design and Characterization of a Stealth Immunoliposome Encapsulating a Large Molecule Biotherapeutic (Antibody)
(2017-04-13)
This thesis project will endeavor to solve the obstacles around synthesis of Immunoliposomes loaded with an antibody therapeutic. Most steps in the preparation of liposomes in most of the methods include harsh conditions ...