Search
Now showing items 1-6 of 6
A Role for DOCK4 in Intestinal Barrier Properties
(2016-02-16)
Restoration of epithelial and endothelial barrier function is critical for tissue homeostasis. Yet, the molecular pathways response for modulating barrier properties remains largely unknown. This study investigates the ...
Characterization of the Effects of IVIg on CNS Inflammation Leading to Non-Classical Disease in a Relapsing Remitting Model of EAE
(2016-10-19)
Intravenous Immunoglobulin (IVIg) is a complex therapeutic used in the treatment of multiple autoimmune and inflammatory diseases. The mechanism of action of IVIg is pleiotropic; there is increasing evidence that modulation ...
Application of Anaerobic Fluorescence Activated Cell Sorting to Isolate and Cultivate Inflammatory Bowel Disease Associated Gut Microbes
(2018-04-13)
The gut microbiome has been an area of intense study over the last decade and numerous studies have highlighted it as an important environmental factor that influences both health and disease. The microbiome has been ...
Development of a High Throughput Flow Cytometry Method to Analyze Changes in Epigenetic Histone Modifications in the Cell
(2018-01-12)
Epigenetic studies commonly include assays such as Chromatin Immunoprecipitation (ChIP), western blotting, and immunofluorescence (IF), which are used to measure changes in chromatin modifications and in DNA methylation ...
The Role of Chemokines CCL19b and CCL25b in T Cell Recruitment Into Melanoma Tumors.
(2017-08-24)
Malignant melanoma is an extremely metastatic cancer that is highly resistant to conventional therapy. One of the developing approaches to address melanoma involves immunotherapy. Immunotherapy involves harnessing the ...