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dc.contributor.authorLaumer, Christopher Een_US
dc.contributor.authorHejnol, Andreasen_US
dc.contributor.authorGiribet, Gonzaloen_US
dc.date.accessioned2015-05-04T15:26:37Z
dc.date.issued2015en_US
dc.identifier.citationLaumer, Christopher E, Andreas Hejnol, and Gonzalo Giribet. 2015. “Nuclear genomic signals of the ‘microturbellarian’ roots of platyhelminth evolutionary innovation.” eLife 4 (1): e05503. doi:10.7554/eLife.05503. http://dx.doi.org/10.7554/eLife.05503.en
dc.identifier.issn2050-084Xen
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:15034859
dc.description.abstractFlatworms number among the most diverse invertebrate phyla and represent the most biomedically significant branch of the major bilaterian clade Spiralia, but to date, deep evolutionary relationships within this group have been studied using only a single locus (the rRNA operon), leaving the origins of many key clades unclear. In this study, using a survey of genomes and transcriptomes representing all free-living flatworm orders, we provide resolution of platyhelminth interrelationships based on hundreds of nuclear protein-coding genes, exploring phylogenetic signal through concatenation as well as recently developed consensus approaches. These analyses robustly support a modern hypothesis of flatworm phylogeny, one which emphasizes the primacy of the often-overlooked ‘microturbellarian’ groups in understanding the major evolutionary transitions within Platyhelminthes: perhaps most notably, we propose a novel scenario for the interrelationships between free-living and vertebrate-parasitic flatworms, providing new opportunities to shed light on the origins and biological consequences of parasitism in these iconic invertebrates. DOI: http://dx.doi.org/10.7554/eLife.05503.001en
dc.language.isoen_USen
dc.publishereLife Sciences Publications, Ltden
dc.relation.isversionofdoi:10.7554/eLife.05503en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398949/pdf/en
dash.licenseLAAen_US
dc.subjectPlatyhelminthesen
dc.subjectphylogenyen
dc.subjectRNA-seqen
dc.subjectparasitismen
dc.subjectotheren
dc.titleNuclear genomic signals of the ‘microturbellarian’ roots of platyhelminth evolutionary innovationen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journaleLifeen
dash.depositing.authorLaumer, Christopher Een_US
dc.date.available2015-05-04T15:26:37Z
dc.identifier.doi10.7554/eLife.05503*
dash.contributor.affiliatedLaumer, Christopher
dash.contributor.affiliatedGiribet, Gonzalo
dc.identifier.orcid0000-0001-8097-8516


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