Fundamentals of Clinical Outcomes Assessment for Spinal Disorders: Study Designs, Methodologies, and Analyses

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Fundamentals of Clinical Outcomes Assessment for Spinal Disorders: Study Designs, Methodologies, and Analyses

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Title: Fundamentals of Clinical Outcomes Assessment for Spinal Disorders: Study Designs, Methodologies, and Analyses
Author: Vavken, Patrick; Ganal-Antonio, Anne Kathleen B.; Shen, Francis H.; Chapman, Jens R.; Samartzis, Dino

Note: Order does not necessarily reflect citation order of authors.

Citation: Vavken, Patrick, Anne Kathleen B. Ganal-Antonio, Francis H. Shen, Jens R. Chapman, and Dino Samartzis. 2015. “Fundamentals of Clinical Outcomes Assessment for Spinal Disorders: Study Designs, Methodologies, and Analyses.” Global Spine Journal 5 (2): 156-164. doi:10.1055/s-0035-1547525. http://dx.doi.org/10.1055/s-0035-1547525.
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Abstract: Study Design A broad narrative review. Objective: Management of spinal disorders is continuously evolving, with new technologies being constantly developed. Regardless, assessment of patient outcomes is key in understanding the safety and efficacy of various therapeutic interventions. As such, evidence-based spine care is an essential component to the armamentarium of the spine specialist in an effort to critically analyze the reported literature and execute studies in an effort to improve patient care and change clinical practice. The following article, part one of a two-part series, is meant to bring attention to the pros and cons of various study designs, their methodological issues, as well as statistical considerations. Methods: An extensive review of the peer-reviewed literature was performed, irrespective of language of publication, addressing study designs and their methodologies as well as statistical concepts. Results: Numerous articles and concepts addressing study designs and their methodological considerations as well as statistical analytical concepts have been reported. Their applications in the context of spine-related conditions and disorders were noted. Conclusion: Understanding the fundamental principles of study designs and their methodological considerations as well as statistical analyses can further advance and improve future spine-related research.
Published Version: doi:10.1055/s-0035-1547525
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369198/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:15035002
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