dc.contributor.author | Gao, Yanfei | en_US |
dc.contributor.author | Chen, Shaoyong | en_US |
dc.date.accessioned | 2015-05-04T15:28:02Z | |
dc.date.issued | 2013 | en_US |
dc.identifier.citation | Gao, Yanfei, and Shaoyong Chen. 2013. “Proline-Directed Androgen Receptor Phosphorylation.” Journal of molecular and genetic medicine : an international journal of biomedical research 7 (3): 75. doi:10.4172/1747-0862.1000075. http://dx.doi.org/10.4172/1747-0862.1000075. | en |
dc.identifier.issn | 1747-0862 | en |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:15035044 | |
dc.description.abstract | The androgen receptor (AR) has been identified for decades and mediates essential steroid functions. Like most of biological molecules, AR functional activities are modulated by post-translational modifications. This review is focused on the reported activities and significance of AR phosphorylation, with particular emphasis on proline-directed serine/threonine phosphorylation that occurs predominantly on the receptor. The marked enrichment of AR phosphorylation in the most diverse N-terminal domain suggests that targeting AR phosphorylation can be synergistic to antagonizing the C-terminal domain by clinical antiandrogens. | en |
dc.language.iso | en_US | en |
dc.relation.isversionof | doi:10.4172/1747-0862.1000075 | en |
dc.relation.hasversion | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389684/pdf/ | en |
dash.license | LAA | en_US |
dc.subject | Androgen receptor | en |
dc.subject | Phosphorylation | en |
dc.subject | Proline-directed serine/threonine phosphorylation | en |
dc.subject | Kinases | en |
dc.subject | Phosphatase | en |
dc.title | Proline-Directed Androgen Receptor Phosphorylation | en |
dc.type | Journal Article | en_US |
dc.description.version | Version of Record | en |
dc.relation.journal | Journal of molecular and genetic medicine : an international journal of biomedical research | en |
dash.depositing.author | Gao, Yanfei | en_US |
dc.date.available | 2015-05-04T15:28:02Z | |
dc.identifier.doi | 10.4172/1747-0862.1000075 | * |
dash.contributor.affiliated | Gao, Yanfei | |