DNA Brick Crystals with Prescribed Depth
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CitationKe, Yonggang, Luvena L. Ong, Wei Sun, Jie Song, Mingdong Dong, William M. Shih, and Peng Yin. 2014. “DNA Brick Crystals with Prescribed Depth.” Nature chemistry 6 (11): 994-1002. doi:10.1038/nchem.2083. http://dx.doi.org/10.1038/nchem.2083.
AbstractWe describe a general framework for constructing two-dimensional crystals with prescribed depth and sophisticated three-dimensional features. These crystals may serve as scaffolds for the precise spatial arrangements of functional materials for diverse applications. The crystals are self-assembled from single-stranded DNA components called DNA bricks. We demonstrate the experimental construction of DNA brick crystals that can grow to micron-size in the lateral dimensions with precisely controlled depth up to 80 nanometers. They can be designed to display user-specified sophisticated three-dimensional nanoscale features, such as continuous or discontinuous cavities and channels, and to pack DNA helices at parallel and perpendicular angles relative to the plane of the crystals.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:16121056
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