Anti-Inflammatory and Immunoregulatory Functions of Artemisinin and Its Derivatives

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Anti-Inflammatory and Immunoregulatory Functions of Artemisinin and Its Derivatives

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Title: Anti-Inflammatory and Immunoregulatory Functions of Artemisinin and Its Derivatives
Author: Shi, Chenchen; Li, Haipeng; Yang, Yifu; Hou, Lifei

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Citation: Shi, Chenchen, Haipeng Li, Yifu Yang, and Lifei Hou. 2015. “Anti-Inflammatory and Immunoregulatory Functions of Artemisinin and Its Derivatives.” Mediators of Inflammation 2015 (1): 435713. doi:10.1155/2015/435713. http://dx.doi.org/10.1155/2015/435713.
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Abstract: Artemisinin and its derivatives are widely used in the world as the first-line antimalarial drug. Recently, growing evidences reveal that artemisinin and its derivatives also possess potent anti-inflammatory and immunoregulatory properties. Meanwhile, researchers around the world are still exploring the unknown bioactivities of artemisinin derivatives. In this review, we provide a comprehensive discussion on recent advances of artemisinin derivatives affecting inflammation and autoimmunity, the underlying molecular mechanisms, and also drug development of artemisinins beyond antimalarial functions.
Published Version: doi:10.1155/2015/435713
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415672/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:16121118
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