dc.contributor.author | Drew, Benjamin | en_US |
dc.date.accessioned | 2015-07-13T19:44:03Z | |
dash.embargo.terms | 2016-05-01 | en_US |
dc.date.created | 2015-05 | en_US |
dc.date.issued | 2015-06-08 | en_US |
dc.date.submitted | 2015 | en_US |
dc.identifier.citation | Drew, Benjamin. 2015. Treatment Patterns, Outcomes, and Patient Satisfaction of Epidermal Superficial Non-Melanoma Skin Cancer at an Academic Dermatologic Surgery Center. Doctoral dissertation, Harvard Medical School. | en_US |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:17295900 | |
dc.description.abstract | Epidermally-limited non melanoma skin cancer (NMSC), defined as superficial basal cell carcinoma and squamous cell carcinomas in-situ, is associated with significant morbidity and cost. This study examined the patterns, outcomes, and satisfaction for NMSC treatment. The study consisted of a retrospective single institution analysis of 550 patients diagnosed with 678 NMSCs treated from Jan 2008 to Mar 2014. A satisfaction survey was then administered to 142 patients from May 2014 to Jun 2014. A total of 329 tumors (49%) were treated with Mohs micrographic surgery (MMS), 292 tumors (43%) with topical medication (TM), and 57 tumors (8%) with cryotherapy (CT). Of the 11 clinical recurrences (2%), 7 (64%) were treated with TM, 2 (18%) with MMS, and 2 (18%) with CT. The difference in recurrence risk (3.3% non-MMS vs. 0.7% MMS) was not significant. Independent predictors for recurrence were tumor diameter greater than 2.0 cm (HR, 5.1 [95% CI, 1.3-19.5]) and immunosuppression (3.6 [1.0-12.5]). Of patients surveyed, 97% who received MMS were satisfied/very satisfied versus 91% who received non-MMS treatment (p=0.092). This study indicates that surgical and non-surgical treatments for NMSC may have more equivalent efficacy than previously reported and a large majority of patients are satisfied with their treatment. | en_US |
dc.format.mimetype | application/pdf | en_US |
dc.language.iso | en | en_US |
dash.license | LAA | en_US |
dc.title | Treatment Patterns, Outcomes, and Patient Satisfaction of Epidermal Superficial Non-Melanoma Skin Cancer at an Academic Dermatologic Surgery Center | en_US |
dc.type | Thesis or Dissertation | en_US |
dash.depositing.author | Drew, Benjamin | en_US |
dc.date.available | 2016-05-02T07:31:19Z | |
thesis.degree.date | 2015 | en_US |
thesis.degree.grantor | Harvard Medical School | en_US |
thesis.degree.level | Doctoral | en_US |
thesis.degree.name | Doctor of Medicine | en_US |
dc.type.material | text | en_US |
dash.identifier.vireo | http://etds.lib.harvard.edu/hms/admin/view/209 | en_US |
dc.description.keywords | Non Melanoma Skin Cancer; Squamous Cell Carcinoma in-situ, Basal Cell Carcinoma, Mohs Micrographic Surgery | en_US |
dash.author.email | benjamin_drew@hms.harvard.edu | en_US |
dash.identifier.drs | urn-3:HUL.DRS.OBJECT:25170953 | en_US |
dash.contributor.affiliated | Drew, Benjamin | |