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    • A Potent α/β-Peptide Analogue of GLP-1 with Prolonged Action in Vivo 

      Johnson, Lisa M.; Barrick, Stacey; Hager, Marlies V.; McFedries, Amanda; Homan, Edwin A.; Rabaglia, Mary E.; Keller, Mark P.; Attie, Alan D.; Saghatelian, Alan; Bisello, Alessandro; Gellman, Samuel H. (American Chemical Society, 2014)
      Glucagon-like peptide-1 (GLP-1) is a natural agonist for GLP-1R, a G protein-coupled receptor (GPCR) on the surface of pancreatic β cells. GLP-1R agoinsts are attractive for treatment of type 2 diabetes, but GLP-1 itself ...