Browsing FAS Scholarly Articles by Author "Qadri, Firdausi"

Now showing items 1-3 of 3

    • Chemoproteomic profiling of host and pathogen enzymes active in cholera 

      Hatzios, Stavroula K.; Abel, Sören; Martell, Julianne; Hubbard, Troy; Sasabe, Jumpei; Munera, Diana; Clark, Lars; Bachovchin, Daniel A.; Qadri, Firdausi; Ryan, Edward T.; Davis, Brigid M.; Weerapana, Eranthie; Waldor, Matthew K. (2016)
      Activity-based protein profiling (ABPP) is a chemoproteomic tool for detecting active enzymes in complex biological systems. We used ABPP to identify secreted bacterial and host serine hydrolases that are active in animals ...

    • High Depth, Whole-Genome Sequencing of Cholera Isolates from Haiti and the Dominican Republic 

      Sealfon, Rachel; Gire, Stephen; Ellis, Crystal Nicole; Calderwood, Stephen Beaven; Qadri, Firdausi; Hensley, Lisa; Kellis, Manolis; Ryan, Edward Thomas; Larocque, Regina Celes; Harris, Jason B.; Sabeti, Pardis Christine (BioMed Central, 2012)
      Background: Whole-genome sequencing is an important tool for understanding microbial evolution and identifying the emergence of functionally important variants over the course of epidemics. In October 2010, a severe cholera ...

    • A variant in long palate, lung and nasal epithelium clone 1 is associated with cholera in a Bangladeshi population 

      Larocque, Regina Celes; Sabeti, Pardis Christine; Duggal, Priya; Chowdhury, Fahima; Khan, Ashraful I.; Lebrun, Lauren M.; Harris, Jason B.; Ryan, Edward Thomas; Qadri, Firdausi; Calderwood, Stephen Beaven (Nature Publishing Group, 2009)
      Vibrio cholerae causes a dehydrating diarrheal illness that can be rapidly fatal in the absence of specific treatment. The organism is an historic scourge and, like similar infectious diseases, may have influenced the ...