Now showing items 10545-10564 of 18256

    • NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes 

      Adams, Drew J.; Ito, Daisuke; Rees, Matthew G.; Seashore-Ludlow, Brinton; Puyang, Xiaoling; Ramos, Alex H.; Cheah, Jaime H.; Clemons, Paul A.; Warmuth, Markus; Zhu, Ping; Shamji, Alykhan F.; Schreiber, Stuart L. (American Chemical Society, 2014)
      The small-molecule probes STF-31 and its analogue compound 146 were discovered while searching for compounds that kill VHL-deficient renal cell carcinoma cell lines selectively and have been reported to act via direct ...
    • Nano-mechanical measurements of protein-DNA interactions with a silicon nitride pulley 

      Shon, Min Ju; Cohen, Adam E. (Oxford University Press, 2016)
      Proteins adhere to DNA at locations and with strengths that depend on the protein conformation, the underlying DNA sequence and the ionic content of the solution. A facile technique to probe the positions and strengths of ...
    • Nano-optic endoscope for high-resolution optical coherence tomography in vivo 

      Pahlevaninezhad, Hamid; Khorasaninejad, Mohammadreza; Huang, Yao-Wei; Shi, Zhujun; Hariri, Lida P.; Adams, David C.; Ding, Vivien; Zhu, Alexander; Qiu, Cheng-Wei; Capasso, Federico; Suter, Melissa (Springer Science and Business Media LLC, 2018-07-30)
    • Nano-Project Qualifying Exam Process: An Intensified Dialogue between Students and Faculty 

      Blitzstein, Joseph Kalmon; Meng, Xiao-Li (American Statistical Association, 2010)
      An effectively designed examination process goes far beyond revealing students’ knowledge or skills. It also serves as a great teaching and learning tool, incentivizing the students to think more deeply and to connect the ...
    • Nano-sized SQUID-on-tip for scanning probe microscopy 

      Finkler, A; Vasyukov, D; Segev, Y; Neeman, L; Anahory, Y; Myasoedov, Y; Rappaport, M L; Huber, M E; Martin, J; Yacoby, Amir; Zeldov, E (IOP Publishing, 2012)
      We present a SQUID of novel design, which is fabricated on the tip of a pulled quartz tube in a simple 3-step evaporation process without need for any additional processing, patterning, or lithography. The resulting devices ...
    • Nano-Thermal Transport Array: An Instrument for Combinatorial Measurements of Heat Transfer in Nanoscale Films 

      McCluskey, Patrick James; Vlassak, Joost J. (Elsevier, 2010)
      The nano-Thermal Transport Array is a silicon-based micromachined device for measuring the thermal properties of nanoscale materials in a high-throughput methodology. The device contains an array of thermal sensors, each ...
    • A nanocrystal-based ratiometric pH sensor for natural pH ranges 

      Somers, Rebecca C.; Lanning, Ryan M.; Snee, Preston T.; Greytak, Andrew B.; Jain, Rakesh K.; Bawendi, Moungi G.; Nocera, Daniel (Royal Society of Chemistry (RSC), 2012)
      A ratiometric fluorescent pH sensor based on CdSe/CdZnS nanocrystal quantum dots (NCs) has been designed for biological pH ranges. The construct is formed from the conjugation of a pH dye (SNARF) to NCs coated with a ...
    • Nanocrystalline Precursors for the Co-Assembly of Crack-Free Metal Oxide Inverse Opals 

      Phillips, Katherine Reece; Shirman, Tanya; Shirman, Elijah; Shneidman, Anna Vitalyevna; Kay, Theresa M.; Aizenberg, Joanna (Wiley, 2018)
      Inorganic microstructured materials are ubiquitous in nature. However, their formation in artificial self‐assembly systems is challenging as it involves a complex interplay of competing forces during and after assembly. ...
    • A nanoelectrode array for obtaining intracellular recordings from thousands of connected neurons 

      Abbott, Jeffrey; Ye, Tianyang; Krenek, Keith; Gertner, Rona S.; Ban, Steven; Kim, Youbin; Qin, Ling; Wu, Wenxuan; Park, Hongkun; Ham, Donhee (Springer Science and Business Media LLC, 2019-09-23)
      Current electrical or optical electrophysiology methods cannot reliably obtain intracellular recordings simultaneously from more than a few tens of neurons. Here, we report a nanoelectrode array that can record action ...
    • Nanoelectronics-Biology Frontier: From Nanoscopic Probes for Action Potential Recording in Live Cells to Three-Dimensional Cyborg Tissues 

      Duan, Xiaojie; Fu, Tian-Ming; Liu, Jia; Lieber, Charles M. (Elsevier, 2013)
      Semiconductor nanowires configured as the active channels of field-effect transistors (FETs) have been used as detectors for high-resolution electrical recording from single live cells, cell networks, tissues and organs. ...
    • Nanofriction in Cavity Quantum Electrodynamics 

      Fogarty, T.; Cormick, C.; Landa, H.; Stojanović, Vladimir M.; Demler, E.; Morigi, Giovanna (American Physical Society, 2015)
      The dynamics of cold trapped ions in a high-finesse resonator results from the interplay between the long-range Coulomb repulsion and the cavity-induced interactions. The latter are due to multiple scatterings of laser ...
    • Nanog-Independent Reprogramming to iPSCs with Canonical Factors 

      Carter, Ava C.; Davis-Dusenbery, Brandi N.; Koszka, Kathryn; Ichida, Justin K.; Eggan, Kevin (Elsevier, 2014)
      Summary It has been suggested that the transcription factor Nanog is essential for the establishment of pluripotency during the derivation of embryonic stem cells and induced pluripotent stem cells (iPSCs). However, ...
    • Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway 

      Xu, Cong; Fan, Zi Peng; Müller, Patrick; Fogley, Rachel; DiBiase, Anthony; Trompouki, Eirini; Unternaehrer, Juli; Xiong, Fengzhu; Torregroza, Ingrid; Evans, Todd; Megason, Sean; Daley, George Quentin; Schier, Alexander F; Young, Richard A.; Zon, Leonard Ira (Elsevier, 2012)
      In mammalian embryonic stem cells, the acquisition of pluripotency is dependent on Nanog, but the in vivo analysis of Nanog has been hampered by its requirement for early mouse development. In an effort to examine the role ...
    • Nanomagnetic Control of Intersystem Crossing 

      Cohen, Adam Ezra (American Chemical Society, 2009)
      A theory is presented for how magnetic nanostructures can catalyze intersystem crossing in molecular radical pairs. Magnetic field gradients near physically realistic nanostructures are strong enough to induce a relative ...
    • Nanometer Patterning with Ice 

      King, Gavin M.; Schurmann, Gregor; Branton, Daniel; Golovchenko, Jene (American Chemical Society, 2005)
      Nanostructures can be patterned with focused electron or ion beams in thin, stable, conformal films of water ice grown on silicon. We use these patterns to reliably fabricate sub-20 nm wide metal lines and exceptionally ...
    • Nanometer-thin solid-state nanopores by cold ion beam sculpting 

      Kuan, Aaron Tzeyang; Golovchenko, Jene Andrew (AIP Publishing, 2012)
      Recent work on protein nanopores indicates that single molecule characterization (including DNA sequencing) is possible when the length of the nanopore constriction is about a nanometer. Solid-state nanopores offer advantages ...
    • Nanometre-scale probing of spin waves using single-electron spins 

      van der Sar, Toeno; Casola, Francesco; Walsworth, Ronald Lee; Yacoby, Amir (Nature Publishing Group, 2015)
      Pushing the frontiers of condensed-matter magnetism requires the development of tools that provide real-space, few-nanometre-scale probing of correlated-electron magnetic excitations under ambient conditions. Here we present ...
    • Nanometre-scale thermometry in a living cell 

      Kucsko, Georg; Maurer, Peter; Yao, Norman Ying; KUBO, MICHAEL; Noh, Hyungi; Lo, P. K.; Park, Hongkun; Lukin, Mikhail D. (Nature Publishing Group, 2013)
      Sensitive probing of temperature variations on nanometre scales is an outstanding challenge in many areas of modern science and technology. In particular, a thermometer capable of subdegree temperature resolution over a ...
    • Nanoparticle Assembly: A Perspective and some Unanswered Questions 

      Kumar, Sanat; Kumaraswamy, Guruswamy; Prasad, Bhagavatula; Bandyopadhyaya, Rajdip; Granick, Steve; Gang, Oleg; Manoharan, Vinothan; Frenkel, Daan; Kotov, Nicholas (Current Science Association, 2017-04-01)
      In early 2016, the Royal Society of Chemistry arranged a meeting on the topic ‘Nanoparticle Assemblies: from Fundamentals to Applications’ which was hosted at IIT-Bombay, Mumbai. The meeting brought several leading nanoscience ...