Browsing FAS Scholarly Articles by Title
Now showing items 1831-1850 of 18292
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The cdx Genes and Retinoic Acid Control the Positioning and Segmentation of the Zebrafish Pronephros
(Public Library of Science, 2007)Kidney function depends on the nephron, which comprises a blood filter, a tubule that is subdivided into functionally distinct segments, and a collecting duct. How these regions arise during development is poorly understood. ... -
Cdx4 Is Dispensable for Murine Adult Hematopoietic Stem Cells but Promotes MLL-AF9-Mediated Leukemogenesis
(Ferrata Storti Foundation (Haematologica), 2010)Background: Cdx4 is a homeobox gene essential for normal blood formation during embryonic development in the zebrafish, through activation of posterior Hox genes. However, its role in adult mammalian hematopoiesis has not ... -
Celebrating Soft Matter's 10th anniversary: Testing the foundations of classical entropy: colloid experiments
(Royal Society of Chemistry (RSC), 2015)By performing experiments on colloids, one can establish that certain definitions of the classical entropy fit the data, while others in the literature do not. -
A celebration of the mathematical work of Glenn Stevens
(Springer Nature, 2015) -
Celebrities’ impact on health-related knowledge, attitudes, behaviors, and status outcomes: protocol for a systematic review, meta-analysis, and meta-regression analysis
(BioMed Central, 2017)Background: Celebrities are highly influential people whose actions and decisions are watched and often emulated by wide audiences. Many celebrities have used their prominent social standing to offer medical advice or ... -
Cell Aging in Relation to Stress Arousal and Cardiovascular Disease Risk Factors
(Elsevier, 2006)We previously reported that psychological stress is linked to and possibly accelerates cellular aging, as reflected by tower PBMC telomerase and shortened tetomeres. Psychological stress is a major risk factor for ... -
Cell Division Cycle 6, a Mitotic Substrate of Polo-Like Kinase 1, Regulates Chromosomal Segregation Mediated by Cyclin-Dependent Kinase 1 and Separase
(Proceedings of the National Academy of Sciences, 2010)Defining the links between cell division and DNA replication is essential for understanding normal cell cycle progression and tumorigenesis. In this report we explore the effect of phosphorylation of cell division cycle 6 ... -
Cell Encapsulation in Sub-mm Sized Gel Modules Using Replica Molding
(Public Library of Science, 2008)For many types of cells, behavior in two-dimensional (2D) culture differs from that in three-dimensional (3D) culture. Among biologists, 2D culture on treated plastic surfaces is currently the most popular method for cell ... -
Cell Migration Driven by Cooperative Substrate Deformation Patterns
(American Physical Society, 2010) -
Cell motility: Turning failure into function
(Springer Nature, 2013)In their search for more favourable environments bacteria choose new directions to explore, usually at random. In a marine bacterium with a single polar flagellum it is now shown that this quest is enhanced by a buckling ... -
Cell Size Regulation in Bacteria
(American Physical Society (APS), 2014)Various bacteria such as the canonical gram negative Escherichia coli or the well-studied gram positive Bacillus subtilis divide symmetrically after they approximately double their volume. Their size at division is not ... -
Cell Type of Origin Influences the Molecular and Functional Properties of Mouse Induced Pluripotent Stem Cells
(Nature Publishing Group, 2010)Induced pluripotent stem cells (iPSCs) have been derived from various somatic cell populations through ectopic expression of defined factors. It remains unclear whether iPSCs generated from different cell types are molecularly ... -
Cell Type-Specific Manipulation with GFP-Dependent Cre Recombinase
(2016)Summary There are many transgenic GFP reporter lines that allow visualization of specific populations of cells. Using such lines for functional studies requires a method that transforms GFP into a molecule that enables ... -
Cell-Cycle Dependent Expression of a Translocation-Mediated Fusion Oncogene Mediates Checkpoint Adaptation in Rhabdomyosarcoma
(Public Library of Science, 2014)Rhabdomyosarcoma is the most commonly occurring soft-tissue sarcoma in childhood. Most rhabdomyosarcoma falls into one of two biologically distinct subgroups represented by alveolar or embryonal histology. The alveolar ... -
Cell-to-cell coupling in engineered pairs of rat ventricular cardiomyocytes: relation between Cx43 immunofluorescence and intercellular electrical conductance
(American Physiological Society, 2012)Gap junctions are composed of connexin (Cx) proteins, which mediate intercellular communication. Cx43 is the dominant Cx in ventricular myocardium, and Cx45 is present in trace amounts. Cx43 immunosignal has been associated ... -
Cellular cooperation with shift updating and repulsion
(Nature Publishing Group, 2015)Population structure can facilitate evolution of cooperation. In a structured population, cooperators can form clusters which resist exploitation by defectors. Recently, it was observed that a shift update rule is an ... -
Cellular Hydraulics Suggests a Poroelastic Cytoplasm Rheology
(Nature Publishing Group, 2013-01-07)The cytoplasm represents the largest part of the cell by volume and hence its rheology sets the rate at which cellular shape change can occur. Recent experimental evidence suggests that cytoplasmic rheology can be described ... -
Cellular Interrogation: Exploiting Cell-to-Cell Variability to Discriminate Regulatory Mechanisms in Oscillatory Signalling
(Public Library of Science, 2016)The molecular complexity within a cell may be seen as an evolutionary response to the external complexity of the cell’s environment. This suggests that the external environment may be harnessed to interrogate the cell’s ... -
Cellular nanoscale stiffness patterns governed by intracellular forces
(Springer Science and Business Media LLC, 2019-06-17)Cell stiffness measurements have led to insights into various physiological and pathological processes. Although many cellular behaviours are influenced by intracellular mechanical forces that also alter the material ... -
Cellular uptake mechanisms and endosomal trafficking of supercharged proteins
(Elsevier BV, 2012)Supercharged proteins can deliver functional macromolecules into the cytoplasm of mammalian cells with potencies that exceed those of cationic peptides. The structural features of supercharged proteins that determine their ...