Browsing FAS Scholarly Articles by Title
Now showing items 4120-4139 of 18292
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A DNA-based molecular probe for optically reporting cellular traction forces
(2014)We developed molecular tension probes (TPs) that report traction forces of adherent cells with high spatial resolution, can be linked to virtually any surface, and obviate monitoring deformations of elastic substrates. TPs ... -
DNA-Binding Specificity Changes in the Evolution of Forkhead Transcription Factors
(Proceedings of the National Academy of Sciences, 2013)The evolution of transcriptional regulatory networks entails the expansion and diversification of transcription factor (TF) families. The forkhead family of TFs, defined by a highly conserved winged helix DNA-binding domain ... -
DNA-templated polymerization of side-chain-functionalized peptide nucleic acid aldehydes
(American Chemical Society (ACS), 2008)The DNA-templated polymerization of synthetic building blocks provides a potential route to the laboratory evolution of sequence-defined polymers with structures and properties not necessarily limited to those of natural ... -
Dnmt1 Has De Novo Activity Targeted to Transposable Elements
(Springer Science and Business Media LLC, 2021-06-17)<jats:title>Abstract</jats:title><jats:p>DNA methylation plays a critical role during development, particularly in repressing retrotransposons. The mammalian methylation landscape is dependent on the combined activities ... -
DNMT1-interacting RNAs block gene specific DNA methylation
(2013)Summary DNA methylation was described almost a century ago. However, the rules governing its establishment and maintenance remain elusive. Here, we present data demonstrating that active transcription regulates levels of ... -
Do Corrupt Governments Receive Less Foreign Aid?
(American Economic Association, 2002)Critics of foreign aid programs argue that these funds often support corrupt governments and inefficient bureaucracies. Supporters argue that foreign aid can be used to reward good governments. This paper documents that ... -
Do DSM-5 Eating Disorder Criteria Overpathologize Normative Eating Patterns among Individuals with Obesity?
(Hindawi Publishing Corporation, 2014)Background. DSM-5 revisions have been criticized in the popular press for overpathologizing normative eating patterns—particularly among individuals with obesity. To evaluate the evidence for this and other DSM-5 critiques, ... -
Do Institutions Cause Growth?
(Springer Science + Business Media, 2004)We revisit the debate over whether political institutions cause economic growth, or whether, alternatively, growth and human capital accumulation lead to institutional improvement. We find that most indicators of institutional ... -
Do Labor Unions Have a Future in the United States?
(Praeger, 2013) -
Do Managerial Objectives Drive Bad Acquisitions?
(Wiley, 1990)This paper documents for a sample of 327 US acquisitions between 1975 and 1987 three forces that systematically reduce the announcement day return of bidding firms. The returns to bidding shareholders are lower when their ... -
Do Password Managers Improve Password Hygiene?
(2022-12-24)Password managers purport to increase users' security by improving password hygiene: generating unique random passwords when users create new accounts, replacing users' weak and reused passwords, and determining which sites ... -
Do the Electrons and Ions in X‐Ray Clusters Share the Same Temperature?
(American Astronomical Society, 1997)The virialization shock around an X-ray cluster primarily heats the ions, since they carry most of the kinetic energy of the infalling gas. Subsequently, the ions share their thermal energy with the electrons through Coulomb ... -
Do Transmission Mechanisms or Social Systems Drive Cultural Dynamics in Socially Structured Populations?
(Elsevier, 2009)Cultural traits spread via multiple mechanisms among individuals within social groups, including via transmission biases that occur when subordinates copy from dominants (prestige transmission), or via common cultural trait ... -
Do treatment manuals undermine youth–therapist alliance in community clinical practice?
(American Psychological Association (APA), 2011)Objective: Some critics of treatment manuals have argued that their use may undermine the quality of the client–therapist alliance. This notion was tested in the context of youth psychotherapy delivered by therapists in ... -
Do Visual Experiences Have Contents?
(Oxford University Press, 2010) -
Do Young Children Understand Relative Value Comparisons?
(Public Library of Science, 2015)Many forms of judgments, such as those used in economic games or measures of social comparison, require understanding relative value, as well as the more complex ability to make comparisons between relative values. To ... -
Doctors and Credentials: The Roots of Uncertainty
(The College of Physicians of Philadelphia, 1984)Since 1870 the course of medical licensing in America has been complicated by a number of forces. Formal licencing and specialty certification have always followed rather than preceeded the trends they were meant to control. ... -
Doctors and the Dangers of Driving
(New England Journal of Medicine (NEJM/MMS), 2014) -
"The Doctors’ Choice Is America’s Choice”: The Physician in US Cigarette Advertisements, 1930-1953
(American Public Health Association, 2006)In the 1930s and 1940s, smoking became the norm for both men and women in the United States, and a majority of physicians smoked. At the same time, there was rising public anxiety about the health risks of cigarette smoking. ... -
Documenting Decline in U.S. Economic Mobility
(American Association for the Advancement of Science (AAAS), 2017-04-24)Economists and other social scientists have long studied intergenerational income mobility, but consistent data linking adult incomes of children and their parents at similar ages over many generations have been unavailable, ...