Now showing items 11819-11838 of 18296

    • p38 MAPK Regulates Expression of Immune Response Genes and Contributes to Longevity in C. elegans 

      Troemel, Emily R; Chu, Stephanie W; Reinke, Valerie; Lee, Siu Sylvia; Ausubel, Frederick M.; Kim, Dennis H (Public Library of Science, 2006)
      The PMK-1 p38 mitogen-activated protein kinase pathway and the DAF-2–DAF-16 insulin signaling pathway control Caenorhabditis elegans intestinal innate immunity. pmk-1 loss-of-function mutants have enhanced sensitivity to ...
    • The p53 response in single cells is linearly correlated to the number of DNA breaks without a distinct threshold 

      Loewer, Alexander; Karanam, Ketki; Mock, Caroline; Lahav, Galit (BioMed Central, 2013)
      Background: The tumor suppressor protein p53 is activated by cellular stress. DNA double strand breaks (DSBs) induce the activation of the kinase ATM, which stabilizes p53 and activates its transcriptional activity. Single ...
    • The Pace of Evolution Across Fitness Valleys 

      Gokhale, Chaitanya S.; Iwasa, Yoh; Nowak, Martin A.; Traulsen, Arne (Elsevier, 2009)
      How fast does a population evolve from one fitness peak to another? We study the dynamics of evolving, asexually reproducing populations in which a certain number of mutations jointly confer a fitness advantage. We consider ...
    • Pacific Exploratory Mission in the tropical Pacific: PEM-Tropics A, August-September 1996 

      Hoell, J. M.; Davis, D. D.; Jacob, Daniel James; Rodgers, M. O.; Newell, R. E.; Fuelberg, H. E.; McNeal, R. J.; Raper, J. L.; Bendura, R. J. (Wiley-Blackwell, 1999)
      The NASA Pacific Exploratory Mission to the Pacific tropics (PEM-Tropics) is the third major field campaign of NASA's Global Tropospheric Experiment (GTE) to study the impact of human and natural processes on the chemistry ...
    • Painting with Drops, Jets, and Sheets 

      Herczynski, Andrzej; Cernuschi, Claude; Mahadevan, Lakshminarayanan (American Institute of Physics, 2011)
      A fluid dynamics analysis of Jackson Pollock’s technique opens his and other artists’ work to quantitative exploration.
    • Pair-instability supernovae at the epoch of reionization 

      Pan, Tony; Kasen, Daniel; Loeb, Abraham (Oxford University Press, 2012)
      Pristine stars with masses between similar to 140 and 260 M? are theoretically predicted to die as pair-instability supernovae. These very massive progenitors could come from Population III (Pop III) stars in the early ...
    • Pair-instability supernovae via collision runaway in young dense star clusters 

      Pan, Tony; Loeb, Abraham; Kasen, Daniel (Oxford University Press, 2012)
      Stars with helium cores between similar to 64 and 133 M? are theoretically predicted to die as pair-instability supernovae. This requires very massive progenitors, which are theoretically prohibited for Pop II/I stars ...
    • Paired Electron Pockets in the Hole-Doped Cuprates 

      Galitski, Victor; Sachdev, Subir (American Physical Society, 2009)
      We propose a theory for the underdoped hole-doped cuprates, focusing on the "nodal-anti-nodal dichotomy" observed in recent experiments. Our theory begins with an ordered antiferromagnetic Fermi liquid with electron and ...
    • Pairing insights in iron-based superconductors from scanning tunneling microscopy 

      Song, Can-Li; Hoffman, Jennifer Eve (Elsevier BV, 2013)
      Scanning tunneling microscopy (STM) has made tremendous progress in the study and understanding of both classical and unconventional superconductors. This has motivated a rapidly growing effort to apply the same techniques ...
    • Pairing instabilities in quasi-two-dimensional Fermi gases 

      Pietilä, Ville; Pekker, David; Nishida, Yusuke; Demler, Eugene (American Physical Society, 2012)
      We study nonequilibrium dynamics of ultracold two-component Fermi gases in low-dimensional geometries after the interactions are quenched from a weakly interacting to a strongly interacting regime. We develop a T-matrix ...
    • Pairing Interactions and Gibbs Adsorption at the Liquid Bi-In Surface: A Resonant X-Ray Reflectivity Study 

      DiMasi, E.; Tostmann, H.; Shpyrko, O. G.; Huber, P.; Ocko, B. M.; Pershan, Peter S.; Deutsch, M.; Berman, L. E. (American Physical Society, 2001)
      Resonant x-ray reflectivity measurements from the surface of liquid Bi22In78 find only a modest surface Bi enhancement, with 35 at.% Bi in the first atomic layer. This is in contrast to the Gibbs adsorption in all liquid ...
    • Pairing of Competitive and Topologically Distinct Regulatory Modules Enhances Patterned Gene Expression 

      Yanai, Itai; Baugh, L Ryan; Smith, Jessica J.; Roehrig, Casey; Shen-Orr, Shai S; Claggett, Julia M; Hill, Andrew A.; Slonim, Donna K; Hunter, Craig P. (Nature Publishing Group, 2008)
      Biological networks are inherently modular, yet little is known about how modules are assembled to enable coordinated and complex functions. We used RNAi and time series, whole-genome microarray analyses to systematically ...
    • Pairwise Comparison and Selection Temperature in Evolutionary Game Dynamics 

      Traulsen, Arne; Pacheco, Jorge M.; Nowak, Martin A. (Elsevier, 2007)
      Recently, the frequency-dependent Moran process has been introduced in order to describe evolutionary game dynamics in finite populations. Here, an alternative to this process is investigated that is based on pairwise ...
    • Pairwise kidney exchange 

      Roth, Alvin E.; Sönmez, Tayfun; Utku Ünver, M. (Elsevier BV, 2005)
      In connection with an earlier paper on the exchange of live donor kidneys (Roth, Sönmez, and ‹Ünver 2004) the authors entered into discussions with New England transplant surgeons and their colleagues in the transplant ...
    • Palaeo-Eskimo Genetic Ancestry and the Peopling of Chukotka and North America 

      Flegontov, Pavel; Rohland-Pinello, Nadin; Mallick, Swapan; Flegontova, Olga; Jeong, Choongwon; Keating, Denise; Lawson, Ann; Oppenheimer, Jonas; Raff, Jennifer; Skoglund, Pontus; Stewardson, Kristin; Vasilyev, Sergey; Veselovskaya, Elizaveta; Hayes, M. Geoffrey; Krause, Johannes; Pinhasi, Ron; Reich, David; Changmai, Piya; Adamski, Nicole; Bolnick, Deborah; Culleton, Brendan; Harper, Thomas; Kennett, Douglas; Kim, Alexander; Lamnidis, Thiseas; Olalde, Iñigo; Potter, Ben; Sattler, Robert; Vajda, Edwards; O’Rourke, Dennis; Schiffels, Stephan; Broomandkhoshbacht, Nasreen; Candilio, Francesca; Friesen, Max; Altınışık, Ezgi (Springer Science and Business Media LLC, 2019-06)
      Paleo-Eskimos were the first people to settle vast regions of the American Arctic around 5,000 years ago, and were subsequently joined and largely displaced around 1,000 years ago by ancestors of present-day Inuit and ...
    • A palaeontological case study for species delimitation in diverging fossil lineages 

      Kimura, Yuri; Flynn, Lawrence John; Jacobs, Louis L. (Informa UK Limited, 2015-10)
      A general lineage concept is widely adopted in studies of species delimitation for extant taxa with DNA sequence data. In the general lineage concept, species are separately evolving metapopulations that acquire sets of ...
    • Paleobiological Perspectives on Early Eukaryotic Evolution 

      Knoll, Andrew Herbert (Cold Spring Harbor Laboratory Press, 2014)
      Eukaryotic organisms radiated in Proterozoic oceans with oxygenated surface waters, but, commonly, anoxia at depth. Exceptionally preserved fossils of red algae favor crown group emergence more than 1200 million years ago, ...
    • Paleobiology of Distinctive Benthic Microfossils from the Upper Proterozoic Limestone-Dolomite "Series," Central East Greenland 

      Knoll, Andrew; Swett, Keene; Golubic, Stjepko; Greene, Julian W. (Botanical Society of America, 1987)
      Populations of <i>Polybessurus bipartitus</i> Fairchild ex Green et al., a large and morphologically distinctive microfossil, occur in silicified carbonates of the Upper Proterozoic (700-800 Ma) Limestone-Dolomite "Series," ...
    • Paleobiology of the Mesoproterozoic-Neoproterozoic Transition: The Sukhaya Tunguska Formation, Turukhansk Uplift, Siberia 

      Sergeev, Vladimir N.; Knoll, Andrew; Petrov, Peter Yu. (Elsevier, 1997)
      Silicified carbonates of the latest Mesoproterozoic Sukhaya Tunguska Formation, northwestern Siberia, contain abundant and diverse permineralized microfossils. Peritidal environments are dominated by microbial mats built ...