Now showing items 18199-18218 of 18256

    • Y Chromosome Mediates Ribosomal DNA Silencing and Modulates the Chromatin State in Drosophila 

      Zhou, Jun; Sackton, Timothy; Martinsen, Lene; Silva, Bernardo Lemos; Eickbush, Thomas H.; Hartl, Daniel L. (Proceedings of the National Academy of Sciences, 2012)
      Although the Drosophila Y chromosome is degenerated, heterochromatic, and contains few genes, increasing evidence suggests that it plays an important role in regulating the expression of numerous autosomal and X-linked ...
    • Y Not a Dead End: Epistatic Interactions Between Y-Linked Regulatory Polymorphisms and Genetic Background Affect Global Gene Expression in Drosophila melanogaster 

      Jiang, Pan-Pan Xueke; Hartl, Daniel L.; Silva, Bernardo Lemos (Genetics Society of America, 2010)
      The Y chromosome, inherited without meiotic recombination from father to son, carries relatively few genes in most species. This is consistent with predictions from evolutionary theory that nonrecombining chromosomes lack ...
    • Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth 

      Cox, Andrew G.; Hwang, Katie L.; Brown, Kristin K.; Evason, Kimberley; Beltz, Sebastian; Tsomides, Allison; O'Connor, Keelin; Galli, Giorgio G.; Yimlamai, Dean; Chhangawala, Sagar; Yuan, Min; Lien, Evan C.; Wucherpfennig, Julia; Nissim, Sahar; Minami, Akihiro; Cohen, David E.; Camargo, Fernando D.; Asara, John M.; Houvras, Yariv; Stainier, Didier Y.R.; Goessling, Wolfram (2016)
      The Hippo pathway is an important regulator of organ size and tumorigenesis. It is unclear, however, how Hippo signaling provides the cellular building blocks required for rapid growth. Here, we demonstrate that transgenic ...
    • YAP-Dependent Proliferation by a Small Molecule Targeting Annexin A2 

      Shalhout, Sophia; Yang, Peng-Yu; Grzelak, Edyta M.; Nutsch, Kayla; Shao, Sida; Zambaldo, Claudio; Iaconelli, Jonathan; Ibrahim, Lara; Stanton, Caroline; Chadwick, Stormi R.; Chen, Emily; DeRan, Michael; Li, Sijia; Hull, Mitchell; Wu, Xu; Chatterjee, Arnab K.; Shen, Weijun; Camargo, Fernando; Schultz, Peter; Bollong, Michael J. (Springer Science and Business Media LLC, 2021-03-15)
      The transcriptional coactivator YAP orchestrates a pro-proliferative transcriptional program that controls the fate of somatic stem cells and the regenerative responses of certain tissues. As such, agents that activate YAP ...
    • Yarrabubba - A Large, Deeply Eroded Impact Structure in the Yilgarn Craton, Western Australia 

      Macdonald, Francis Alexander; Bunting, John A.; Cina, Sara E. (Elsevier, 2003)
      Yarrabubba is a newly discovered impact structure situated within the complex granite^greenstone terrain of the Yilgarn Craton. Shock-metamorphic effects including shatter cones, planar deformation features in quartz grains, ...
    • A Year-Long Plateau in the Late-Time Near-Infrared Light Curves of Type Ia Supernovae 

      Graur, Or; Maguire, K; Ryan, R; Nicholl, Margaret; Avelino, Arturo; Riess, A; Shingles, L; Seitenzahl, I; Fisher, Robert (Springer Science and Business Media LLC, 2019-10-07)
      The light curves of Type Ia supernovae are routinely used to constrain cosmology models. Driven by radioactive decay of 56Ni, the light curves steadily decline over time, but >150 days after explosion, the near-infrared ...
    • Yeast Pch2 promotes domainal axis organization, timely recombination progression, and arrest of defective recombinosomes during meiosis 

      Börner, G. Valentin; Barot, Aekam; Kleckner, Nancy (National Academy of Sciences, 2008)
      We show that, during budding yeast meiosis, axis ensemble Hop1/Red1 and synaptonemal complex (SC) component Zip1 tend to occur in alternating strongly staining domains. The widely conserved AAA+-ATPase Pch2 mediates this ...
    • Yeats and Modernism 

      Albright, Daniel (Cambridge University Press, 2006)
      When Yeats died in January 1939, he quickly became the ghost that haunted Modernism. First to register the shade's presence was W. H. Auden, who wrote his famous elegy “In Memory of W. B. Yeats” in February 1939: Now he ...
    • Yeats and Science Fiction 

      Albright, Daniel (University of Notre Dame Press, 1996)
      The young Yeats spent some years editing the poems of William Blake, and Yeats inherited much of Blake’s contempt for science, Blake’s sense that Newton was the devil who murdered the living cosmos and substituted dead ...
    • Yeats, A Vision, and Art History 

      Albright, Daniel (한국예이츠학회 [The Yeats Society of Korea], 2011)
      Yeats worried that his poetry might be destroyed if he wandered too far down what he called the hodos chameliontos, the chameleon road, in which the imagination became so replete, overstimulated, that it kept producing ...
    • Yeats, Pound, Asia, and the Music of the Body 

      Albright, Daniel (2012-07-25)
      In June 2009 news appeared concerning a 33,000-year-old flute, found in a cave in southern Germany, made of the wing bone of a griffon vulture. The idea that the most profound art comes from the innermost recesses of the ...
    • A Yet Deeper Well: ‘Kubla Khan,’ Wookey Hole, Cain 

      Engell, James (Temple University Department of English, 1995)
    • Yield Spreads and Interest Rate Movements: A Bird's Eye View 

      Campbell, John; Shiller, Robert (Blackwell Publishing, 1991)
      This paper examines postwar U.S. term structure data and finds that for almost any combination of maturities between one month and ten years, a high yield spread between a longer-term and a shorter-term interest rate ...
    • Ynot: Dependent Types for Imperative Programs 

      Nanevski, Aleksandar; Morrisett, John Gregory; Shinnar, Avraham Ever; Govereau, Paul; Birkedal, Lars (Association for Computing Machinery, 2008)
      We describe an axiomatic extension to the Coq proof assistant, that supports writing, reasoning about, and extracting higher-order, dependently-typed programs with side-effects. Coq already includes a powerful functional ...
    • You Are What You Read 

      Price, Leah (H.J. Raymond & Co., 2007)
    • You Can't Always Get What You Need: Organizational Determinants of Diversity Programs 

      Dobbin, Frank; Kim, Soohan; Kalev, Alexandra (Sage Publications, 2011)
      While some U.S. corporations have adopted a host of diversity management programs, many have done little or nothing. We explore the forces promoting six diversity programs in a national sample of 816 firms over 23 years. ...
    • “You Do It!”: Going-to-Bed Books and the Scripts of Children's Literature 

      Bernstein, Robin (Modern Language Association (MLA), 2020-10)
      This essay uses performance theory to intervene in a decades-long debate about a characteristic of children's literature: it is the only major category of literature written by one group (adults) for another (children). ...
    • Young Children Consider Merit when Sharing Resources with Others 

      Kanngiesser, Patricia; Warneken, Felix (Public Library of Science, 2012)
      Merit is a key principle of fairness: rewards should be distributed according to how much someone contributed to a task. Previous research suggests that children have an early ability to take merit into account in third-party ...
    • Young children proactively remedy unnoticed accidents 

      Warneken, Felix (Elsevier BV, 2013)
      Human adults will sometimes help without being asked to help, including in situations in which the helpee is oblivious to the problem and thus provides no communicative or behavioral cues that intervention is necessary. ...