Now showing items 334-353 of 14421

    • Alone in the Crowd: The Structure and Spread of Loneliness in a Large Social Network 

      Cacioppo, John T.; Fowler, James H.; Christakis, Nicholas Alexander (American Psychological Association, 2009)
      The discrepancy between an individual’s loneliness and the number of connections in a social network is well documented, yet little is known about the placement of loneliness within, or the spread of loneliness through, ...
    • Als wär’ es ein Stuck von uns . . . German Politics and Society Traverses Twenty Years of United Germany 

      Maier, Charles S. (Berghahn Journals, 2010)
      This essay looks at postunification Germany through the pages of German Politics and Society. The articles published during this period reveal the evolution of intellectuals' understanding of the unified country—concerns ...
    • ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networks 

      Ho, Ritchie; Sances, Samuel; Gowing, Genevieve; Amoroso, Mackenzie Weygandt; O'Rourke, Jacqueline G.; Sahabian, Anais; Wichterle, Hynek; Baloh, Robert H.; Sareen, Dhruv; Svendsen, Clive N. (2016)
      Modeling Amyotrophic Lateral Sclerosis (ALS) with human induced pluripotent stem cells (iPSCs) aims to reenact embryogenesis, maturation, and aging of spinal motor neurons (spMNs) in vitro. As the maturity of spMNs grown ...
    • ALS-causative mutations in FUS/TLS confer gain- and loss-of-function by altered association with SMN and U1-snRNP 

      Sun, Shuying; Ling, Shuo-Chien; Qiu, Jinsong; Albuquerque, Claudio P.; Zhou, Yu; Tokunaga, Seiya; Li, Hairi; Qiu, Haiyan; Bui, Anh; Yeo, Gene W.; Huang, Eric J.; Eggan, Kevin; Zhou, Huilin; Fu, Xiang-Dong; Lagier-Tourenne, Clotilde; Cleveland, Don W. (2015)
      The RNA-binding protein FUS/TLS, mutation in which is causative of the fatal motor neuron disease ALS, is demonstrated to directly bind to the U1-snRNP and SMN complexes. ALS-causative mutations in FUS/TLS are shown to ...
    • Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model 

      Obaldía III, Nicanor; Dow, Geoffrey S.; Gerena, Lucia; Kyle, Dennis; Otero, William; Mantel, Pierre-Yves; Baro, Nicholas; Daniels, Rachel; Mukherjee, Angana; Childs, Lauren M.; Buckee, Caroline; Duraisingh, Manoj T.; Volkman, Sarah K.; Wirth, Dyann F.; Marti, Matthias (Nature Publishing Group, 2016)
      Infections with Plasmodium falciparum, the most pathogenic of the Plasmodium species affecting man, have been reduced in part due to artemisinin-based combination therapies. However, artemisinin resistant parasites have ...
    • Altered intrinsic functional coupling between core neurocognitive networks in Parkinson's disease 

      Putcha, Deepti; Ross, Robert S.; Cronin-Golomb, Alice; Janes, Amy C.; Stern, Chantal E. (Elsevier, 2015)
      Parkinson's disease (PD) is largely attributed to disruptions in the nigrostriatal dopamine system. These neurodegenerative changes may also have a more global effect on intrinsic brain organization at the cortical level. ...
    • Alternating layer addition approach to CdSe/CdS core/shell quantum dots with near-unity quantum yield and high on-time fractions 

      Greytak, Andrew B.; Allen, Peter M.; Liu, Wenhao; Zhao, Jing; Young, Elizabeth R.; Popovic, Zoran; Walker, Brian J.; Nocera, Daniel; Bawendi, Moungi G. (Royal Society of Chemistry (RSC), 2012)
      We report single-particle photoluminescence (PL) intermittency (blinking) with high on-time fractions in colloidal CdSe quantum dots (QD) with conformal CdS shells of 1.4 nm thickness, equivalent to approximately 4 CdS ...
    • An alternative conception of tree-adjoining derivation 

      Schabes, Yves; Shieber, Stuart (Association for Computational Linguistics, 1992)
      The precise formulation of derivation for tree-adjoining grammars has important ramifications for a wide variety of uses of the formalism, from syntactic analysis to semantic interpretation and statistical language modeling. ...
    • An Alternative Conception of Tree-Adjoining Derivation 

      Schabes, Yves; Shieber, Stuart (MIT Press, 1994)
      The precise formulation of derivation for tree-adjoining grammars has important ramifications for a wide variety of uses of the formalism, from syntactic analysis to semantic interpretation and statistical language modeling. ...
    • Alternative Models for Moment Inequalities 

      Pakes, Ariel (Econometric Society, 2010)
      Behavioral choice models generate inequalities which, when combined with additional assumptions, can be used as a basis for estimation. This paper considers two sets of such assumptions and uses them in two empirical ...
    • An Alternative to Ceremonial Negligence (Catullus 68.73-78) 

      Thomas, Richard F. (Harvard University Press, 1978)
    • Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci 

      De Jager, Philip Lawrence; Srivastava, Gyan; Lunnon, Katie; Burgess, Jeremy; Schalkwyk, Leonard C; Yu, Lei; Eaton, Matthew L; Keenan, Brendan T; Ernst, Jason; McCabe, Cristin; Tang, Anna; Raj, Towfique; Replogle, Joseph; Brodeur, Wendy; Gabriel, Stacey; Chai, High S; Younkin, Curtis; Younkin, Steven G; Zou, Fanggeng; Szyf, Moshe; Epstein, Charles B; Schneider, Julie A; Bernstein, Bradley E.; Meissner, Alexander; Ertekin-Taner, Nilufer; Chibnik, Lori; Kellis, Manolis; Mill, Jonathan; Bennett, David A (Nature Publishing Group, 2014)
      We used a collection of 708 prospectively collected autopsied brains to assess the methylation state of the brain's DNA in relation to Alzheimer's disease (AD). We found that the level of methylation at 71 of the 415,848 ...
    • Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect 

      Demetrius, Lloyd A.; Magistretti, Pierre J.; Pellerin, Luc (Frontiers Media S.A., 2015)
      Epidemiological and biochemical studies show that the sporadic forms of Alzheimer's disease (AD) are characterized by the following hallmarks: (a) An exponential increase with age; (b) Selective neuronal vulnerability; (c) ...
    • Amazon Rain Forest Subcanopy Flow and the Carbon Budget: Santarém LBA-ECO Site 

      Tóta, Julio; Fitzjarrald, David R.; Staebler, Ralf M.; Sakai, Ricardo K.; Moraes, Osvaldo M. M.; Acevedo, Otávio C.; Wofsy, Steven; Manzi, Antonio O. (American Geophysical Union, 2008)
      Horizontal and vertical CO<sub>2</sub> fluxes and gradients were made in an Amazon tropical rain forest, the Tapajós National Forest Reserve (FLONA-Tapajós: 54°58′W, 2°51′S). Two observational campaigns in 2003 and 2004 ...
    • Ambient Pressure, Low-Temperature Synthesis and Characterization of Colloidal InN Nanocrystals 

      Hsieh, Jennifer C.; Yun, Dong Soo; Hu, Evelyn; Belcher, Angela M. (Royal Society of Chemistry, 2010)
      Highly soluble, non-aggregated colloidal wurtzite InN nanocrystals were obtained through an ambient pressure, low-temperature method followed by post-synthesis treatment with nitric acid.
    • Ambient Pyrite in Precambrian Chert: New Evidence and a Theory 

      Knoll, Andrew Herbert; Barghoorn, Elso S. (National Academy of Sciences, 1974)
      Ambient pyrites of two distinct types were described from middle Precambrian rocks of the Lake Superior area. A new class of this phenomenon is here described from middle Precambrian chert from western Australia. The newly ...
    • Ambiguity of “intention” 

      Scanlon, Thomas Michael (Cambridge University Press (CUP), 2010)
      Knobe reports that subjects’ judgments of whether an agent did something intentionally vary depending on whether the outcome in question was seen by them as good or as bad. He concludes that subjects’ moral views affect ...
    • Ambivalence About Equality in the United States or, Did Tocqueville Get it Wrong and Why Does that Matter? 

      Hochschild, Jennifer L. (Springer Verlag, 2006)
      Alexis de Tocqueville believed that “democratic peoples’... passion for equality is ardent, insatiable, eternal, and invincible.” This article examines whether and under what conditions residents of the United States ...
    • Amenability, Poincaré Series and Quasiconformal Maps 

      McMullen, Curtis T. (Springer Verlag, 1989)
      Any covering \(Y \rightarrow X\) of a hyperbolic Riemann surface\(X\) of finite area determines an inclusion of Teichmüller spaces \(Teich(X) \hookrightarrow Teich(Y)\). We show this map is an isometry for the Teichmüller ...