Browsing FAS Scholarly Articles by Keyword "Caenorhabditis elegans"

Now showing items 1-6 of 6

    • Automatic Categorization of Diverse Experimental Information in the Bioscience Literature 

      Fang, Ruihua; Schindelman, Gary; Auken, Kimberly Van; Fernandes, Jolene; Chen, Wen; Wang, Xiaodong; Davis, Paul; Tuli, Mary Ann; Marygold, Steven J; Millburn, Gillian; Matthews, Beverley; Zhang, Haiyan; Brown, Nick; Gelbart, William Martin; Sternberg, Paul W (BioMed Central, 2012)
      Background: Curation of information from bioscience literature into biological knowledge databases is a crucial way of capturing experimental information in a computable form. During the biocuration process, a critical ...

    • Chemistry and the Worm: Caenorhabditis elegans as a Platform for Integrating Chemical and Biological Research 

      Hulme, S. Elizabeth; Whitesides, George McClelland (Wiley-Blackwell, 2011)
      This Review discusses the potential usefulness of the worm Caenorhabditis elegans as a model organism for chemists interested in studying living systems. C. elegans, a 1 mm long roundworm, is a popular model organism in ...

    • The Core Apoptotic Executioner Proteins CED-3 and CED-4 Promote Neuronal Regeneration in Caenorhabditis Elegans 

      Pinan-Lucarre, Berangere; Gabel, Christopher V.; Reina, Christopher P.; Hulme, S. Elizabeth; Shevkopylas, Sergey S.; Slone, R. Daniel; Xue, Jian; Qiao, Yujie; Weisberg, Sarah; Roodhouse, Kevin; Sun, Lin; Whitesides, George M.; Samuel, Aravinthan DT; Drisocll, Monica (Public Library of Science, 2012)
      A critical accomplishment in the rapidly developing field of regenerative medicine will be the ability to foster repair of neurons severed by injury, disease, or microsurgery. In C. elegans, individual visualized axons can ...

    • Dopamine Signaling Is Essential for Precise Rates of Locomotion by C. elegans 

      Omura, Daniel T.; Clark, Damon A.; Samuel, Aravinthan DT; Horvitz, H. Robert (Public Library of Science, 2012)
      Dopamine is an important neuromodulator in both vertebrates and invertebrates. We have found that reduced dopamine signaling can cause a distinct abnormality in the behavior of the nematode C. elegans, which has only eight ...

    • Neurobiology of Caenorhabditis elegans Locomotion: Where Do We Stand? 

      Gjorgjieva, Julijana; Biron, David; Haspel, Gal (Oxford University Press, 2014)
      Animals use a nervous system for locomotion in some stage of their life cycle. The nematode Caenorhabditis elegans, a major animal model for almost all fields of experimental biology, has long been used for detailed studies ...

    • Whole Animal Automated Platform for Drug Discovery against Multi-Drug Resistant Staphylococcus aureus 

      Rajamuthiah, Rajmohan; Fuchs, Beth Burgwyn; Jayamani, Elamparithi; Kim, Younghoon; Larkins-Ford, Jonah; Conery, Annie; Ausubel, Frederick M.; Mylonakis, Eleftherios (Public Library of Science, 2014)
      Staphylococcus aureus, the leading cause of hospital-acquired infections in the United States, is also pathogenic to the model nematode Caenorhabditis elegans. The C. elegans-S. aureus infection model was previously carried ...