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    • Chromatin Loops as Allosteric Modulators of Enhancer-Promoter Interactions 

      Doyle, Boryana; Fudenberg, Geoffrey; Imakaev, Maxim; Mirny, Leonid A. (Public Library of Science, 2014)
      The classic model of eukaryotic gene expression requires direct spatial contact between a distal enhancer and a proximal promoter. Recent Chromosome Conformation Capture (3C) studies show that enhancers and promoters are ...