Browsing FAS Scholarly Articles by Keyword "cell fate"

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    • Broadly heterogeneous activation of the master regulator for sporulation in Bacillus subtilis 

      Chastanet, A.; Vitkup, D.; Yuan, Guocheng; Norman, Thomas Maxwell; Liu, Jun; Losick, Richard M. (Proceedings of the National Academy of Sciences, 2010)
      A model system for investigating how developmental regulatory networks determine cell fate is spore formation in Bacillus subtilis. The master regulator for sporulation is Spo0A, which is activated by phosphorylation via ...

    • LHX2 Interacts with the NuRD Complex and Regulates Cortical Neuron Subtype Determinants Fezf2 and Sox11 

      Muralidharan, Bhavana; Khatri, Zeba; Maheshwari, Upasana; Gupta, Ritika; Roy, Basabdatta; Pradhan, Saurabh J.; Karmodiya, Krishanpal; Padmanabhan, Hari; Shetty, Ashwin S.; Balaji, Chinthapalli; Kolthur-Seetharam, Ullas; Macklis, Jeffrey D.; Galande, Sanjeev; Tole, Shubha (Society for Neuroscience, 2017)
      In the developing cerebral cortex, sequential transcriptional programs take neuroepithelial cells from proliferating progenitors to differentiated neurons with unique molecular identities. The regulatory changes that occur ...