Browsing FAS Scholarly Articles by Keyword "codon use"

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    • Large-Effect Beneficial Synonymous Mutations Mediate Rapid and Parallel Adaptation in a Bacterium 

      Agashe, Deepa; Sane, Mrudula; Phalnikar, Kruttika; Diwan, Gaurav D.; Habibullah, Alefiyah; Martinez-Gomez, Norma Cecilia; Sahasrabuddhe, Vinaya; Polachek, William; Wang, Jue; Chubiz, Lon M.; Marx, Christopher J. (Oxford University Press, 2016)
      Contrary to previous understanding, recent evidence indicates that synonymous codon changes may sometimes face strong selection. However, it remains difficult to generalize the nature, strength, and mechanism(s) of such ...