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    • Cyclic Strain Induces Dual-Mode Endothelial-Mesenchymal Transformation of the Cardiac Valve 

      Balachandran, Kartik; Alford, Patrick W.; Wylie-Sears, Jill; Goss, Josue; Grosberg, Anna; Bischoff, Joyce E.; Aikawa, Elena; Levine, Robert A.; Parker, Kevin Kit (Proceedings of the National Academy of Sciences, 2011)
      Endothelial-mesenchymal transformation (EMT) is a critical event for the embryonic morphogenesis of cardiac valves. Inducers of EMT during valvulogenesis include VEGF, TGF-β1, and wnt/β-catenin (where wnt refers to the ...