Now showing items 1-3 of 3

    • Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination 

      Mahan, Alison E.; Jennewein, Madeleine F.; Suscovich, Todd; Dionne, Kendall; Tedesco, Jacquelynne; Chung, Amy W.; Streeck, Hendrik; Pau, Maria; Schuitemaker, Hanneke; Francis, Don; Fast, Patricia; Laufer, Dagna; Walker, Bruce D.; Baden, Lindsey; Barouch, Dan H.; Alter, Galit (Public Library of Science, 2016)
      Antibody effector functions, such as antibody-dependent cellular cytotoxicity, complement deposition, and antibody-dependent phagocytosis, play a critical role in immunity against multiple pathogens, particularly in the ...
    • Minimally Symptomatic Infection in an Ebola ‘Hotspot’: A Cross-Sectional Serosurvey 

      Richardson, Eugene T.; Kelly, J. Daniel; Barrie, Mohamed Bailor; Mesman, Annelies W.; Karku, Sahr; Quiwa, Komba; Marsh, Regan H.; Koedoyoma, Songor; Daboh, Fodei; Barron, Kathryn P.; Grady, Michael; Tucker, Elizabeth; Dierberg, Kerry L.; Rutherford, George W.; Barry, Michele; Jones, James Holland; Murray, Megan B.; Farmer, Paul E. (Public Library of Science, 2016)
      Introduction: Evidence for minimally symptomatic Ebola virus (EBOV) infection is limited. During the 2013–16 outbreak in West Africa, it was not considered epidemiologically relevant to published models or projections of ...
    • Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection 

      Adnan, Sama; Reeves, R. Keith; Gillis, Jacqueline; Wong, Fay E.; Yu, Yi; Camp, Jeremy V.; Li, Qingsheng; Connole, Michelle; Li, Yuan; Piatak, Michael; Lifson, Jeffrey D.; Li, Wenjun; Keele, Brandon F.; Kozlowski, Pamela A.; Desrosiers, Ronald C.; Haase, Ashley T.; Johnson, R. Paul (Public Library of Science, 2016)
      Defining the correlates of immune protection conferred by SIVΔnef, the most effective vaccine against SIV challenge, could enable the design of a protective vaccine against HIV infection. Here we provide a comprehensive ...