Browsing FAS Scholarly Articles by Keyword "Coreceptors"
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Production of Mucosally Transmissible SHIV Challenge Stocks from HIV-1 Circulating Recombinant Form 01_AE env Sequences
(Public Library of Science, 2016)Simian-human immunodeficiency virus (SHIV) challenge stocks are critical for preclinical testing of vaccines, antibodies, and other interventions aimed to prevent HIV-1. A major unmet need for the field has been the lack ... -
TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection
(Public Library of Science, 2016)While T cell immunity initially limits Mycobacterium tuberculosis infection, why T cell immunity fails to sterilize the infection and allows recrudescence is not clear. One hypothesis is that T cell exhaustion impairs ...